SynthesisReproductive biology and endocrinology : RB&E2023
Time interval between hCG administration and oocyte retrieval and ART outcomes: an updated systematic review and meta-analysis.
Synthesis in Reproductive biology and endocrinology : RB&E, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Changing the route of GnRH administration according to the initial cyclic phase of the Ovsynch protocol may optimize reproductive outcomes in dairy cows.BMC veterinary research · 2026Article
- Effects of hCG-to-oocyte retrieval interval on oocyte performances in women with polycystic ovary syndrome undergoing progestin-primed ovarian stimulation: a retrospective cohort trial.Journal of assisted reproduction and genetics · 2026Article
- The estradiol-to-periovulatory follicle ratio (E2/N16) as a marker of follicular endocrine efficiency and embryological outcomes in ART cycles.Frontiers in endocrinology · 2026Observational
- Article
- Determination of the optimal follicle size at the time of trigger in patients with diminished ovarian reserve undergoing ICSI cycle.Journal of ovarian research · 2025Article
- Embryo Cryopreservation Strategy May Improve Live Birth for Women Underwent In Vitro Maturation After Early Oocyte Retrieval: A Retrospective Cohort Study.Reproductive sciences (Thousand Oaks, Calif.) · 2025Article
- The Effect of Trigger-to-Retrieval Time Interval on Assisted Reproductive Technology Outcomes in Patients with Poor Ovarian Response : The Effect of Trigger-to-Retrieval Time Interval on Assisted Reproductive Technology Outcomes.Galen medical journal · 2025Article
- Assisted Reproductive Technology and Disease Management in Infertile Women with Multiple Sclerosis.CNS drugs · 2023Review
- Revisiting the Trigger-to-Oocyte Retrieval Interval: A Machine Learning-Guided Strategy for Improving Oocyte Yield in Diminished Ovarian Reserve.Reproductive medicine and biologyArticle
- Clinical Outcomes of Postponing Oocyte Retrieval Beyond 40 h After Trigger With Diclofenac Pretreatment Compared With the Routine Paradigm: A Retrospective Propensity Score-Matched Study.Reproductive medicine and biologyArticle
- The quality of human eggs and its pre-IVF incubation.Reproductive medicine and biologyReview
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
research questionTo explore whether prolonged hCG-ovum pickup interval improves assisted reproductive technology outcomes.
designCENTRAL, CNKI, Cochrane Systematic Reviews, EMBASE, MEDLINE, PUBMED, and Web of Science up to May 13 2023 were searched for studies reporting associations between hCG-ovum pickup intervals and assisted reproductive technology outcomes. Intervention types included short (≤ 36 h) and long (> 36 h) hCG-ovum pickup intervals in assisted reproductive technology cycles. All outcomes were based upon only fresh embryo transfers. Primary outcome is defined as the clinical pregnancy rate. Data were pooled using random-effects models. Heterogeneity was assessed using the I 2 statistics.
resultsTwelve studies were included in the meta-analysis, including five retrospective cohort studies, one prospective cohort study, and six randomized or quasi-randomized controlled trials. The short and long interval groups had similar oocyte maturation rates, fertilization rate and high-quality embryo rate (OR, 0.69; 95% CI, 0.45-1.06; I 2 = 91.1%, OR, 0.88; 95% CI, 0.77-1.0; I 2 = 44.4% and OR, 1.05; 95% CI, 0.95-1.17; I 2 = 8.6%, respectively). The clinical pregnancy rates in the long retrieval group were significantly higher than in the short retrieval group (OR, 0.66; 95% CI, 0.45-0.95; I 2 = 35.4%). The groups had similar miscarriage and live birth rates (OR, 1.92; 95% CI, 0.66-5.60; I 2 = 0.0% and OR, 0.50; 95% CI, 0.24-1.04; I 2 = 0.0%, respectively).
conclusionsThe clinical pregnancy rates can be increased by prolonging the hCG-ovum pickup interval, which would help us develop more reasonable time schedules for fertility centers and patients. META-ANALYSIS REGISTRATION: PROSPERO CRD42022310006 (28 Apr 2022).
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