Evidence map›Paper›PMID 37400547›Full record

ArticleScientific reports2023

Healthcare costs after kidney transplantation compared to dialysis based on propensity score methods and real world longitudinal register data from Sweden.

Ye Zhang, Ulf-G Gerdtham, Helena Rydell, Torbjörn Lundgren, Johan Jarl

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Allograft nephrectomy: a systematic review of immunological consequences and management of immunosuppressants.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Xenotransplantation in Nephrology: A Narrative Review.Journal of personalized medicine · 2026
    Review
  6. Exploring the challenges: main contraindications in organ donation in ColombiaBiomedica : revista del Instituto Nacional de Salud · 2026
    Article
  7. Article
  8. Predicting EQ-5D-3L utility values from clinical data in a prospective cohort of kidney transplant recipients.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
    Observational
  9. Article
  10. Article
  11. Article
  12. Cost-effectiveness of eCPR: accounting for organ donation.Critical care (London, England) · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ye ZhangPopulation and Development Research Center, Renmin University of China, Beijing, 100872, China.
Ulf-G GerdthamHealth Economics Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.
Helena RydellDepartment of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Huddinge, Sweden.
Torbjörn LundgrenDepartment of Clinical Science, Division of Transplantation Surgery, Intervention and Technology (CLINTEC), H9, Karolinska Institutet, Stockholm, Sweden.
Johan JarlHealth Economics Unit, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden. johan.jarl@med.lu.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to estimate the healthcare costs of kidney transplantation compared with dialysis using a propensity score approach to handle potential treatment selection bias. We included 693 adult wait-listed patients who started renal replacement therapy between 1998 and 2012 in Region Skåne and Stockholm County Council in Sweden. Healthcare costs were measured as annual and monthly healthcare expenditures. In order to match the data structure of the kidney transplantation group, a hypothetical kidney transplant date of persons with dialysis were generated for each dialysis patient using the one-to-one nearest-neighbour propensity score matching method. Applying propensity score matching and inverse probability-weighted regression adjustment models, the potential outcome means and average treatment effect were estimated. The estimated healthcare costs in the first year after kidney transplantation were €57,278 (95% confidence interval (CI) €54,467-60,088) and €47,775 (95% CI €44,313-51,238) for kidney transplantation and dialysis, respectively. Thus, kidney transplantation leads to higher healthcare costs in the first year by €9,502 (p = 0.066) compared to dialysis. In the following two years, kidney transplantation is cost saving [€36,342 (p < 0.001) and €44,882 (p < 0.001)]. For patients with end-stage renal disease, kidney transplantation reduces healthcare costs compared with dialysis over three years after kidney transplantation, even though the healthcare costs are somewhat higher in the first year. Relating the results of existing estimates of costs and health benefits of kidney transplantation shows that kidney transplantation is clearly cost-effective compared to dialysis in Sweden.

Indexed as

Kidney Failure, ChronicKidney TransplantationAdultHealth Care CostsHumansPropensity ScoreRenal DialysisSweden

Identifiers

PMID37400547
PMCPMC10318027

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.