ArticleNature communications2023
Cucurbit[8]uril-based water-dispersible assemblies with enhanced optoacoustic performance for multispectral optoacoustic imaging.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Preparation of an activatable benzothiadiazole-based nanoprobe for multispectral optoacoustic and NIR-II fluorescence dual-mode imaging of liver injury.Nature protocols · 2026Review
- Facile Preparation of a Poly[2]Catenane Network Using Self-Assembled [2]Catenane Unit.Angewandte Chemie (International ed. in English) · 2026Article
- High-Resolution Multispectral Photovoltaic Imagers from Visible to Short-Wave Infrared.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Temperature-Responsive Supramolecular Chiral Switch Achieved by Macrocyclic Confinement.JACS Au · 2026Article
- Multi-wavelength graph convolutional network for high-performance sparse multispectral optoacoustic tomography.Photoacoustics · 2025Article
- Chiral macrocycles forming high-affinity host-guest homoternary complexes for chiral discrimination and amplified circularly polarized luminescence.Nature communications · 2025Article
- Multiplex imaging of amyloid-β plaques dynamics in living brains with quinoline-malononitrile-based probes.Nature biomedical engineering · 2025Article
- Unnatural Triggers Converted From Tetrazine-Attached Sialic Acid for Activation of Optoacoustic Imaging-Guided Cancer Theranostics.Angewandte Chemie (International ed. in English) · 2025Article
- Recent advances in photothermal nanomaterials for ophthalmic applications.Beilstein journal of nanotechnology · 2025Review
- An "AND" logic gate-based supramolecular therapeutic nanoplatform for combatting drug-resistant non-small cell lung cancer.Science advances · 2024Article
- Supramolecular interaction in the action of drug delivery systems.Chemical science · 2024Review
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Organic small-molecule contrast agents have attracted considerable attention in the field of multispectral optoacoustic imaging, but their weak optoacoustic performance resulted from relatively low extinction coefficient and poor water solubility restrains their widespread applications. Herein, we address these limitations by constructing supramolecular assemblies based on cucurbit[8]uril (CB[8]). Two dixanthene-based chromophores (DXP and DXBTZ) are synthesized as the model guest compounds, and then included in CB[8] to prepare host-guest complexes. The obtained DXP-CB[8] and DXBTZ-CB[8] display red-shifted and increased absorption as well as decreased fluorescence, thereby leading to a substantial enhancement in optoacoustic performance. Biological application potential of DXBTZ-CB[8] is investigated after co-assembly with chondroitin sulfate A (CSA). Benefiting from the excellent optoacoustic property of DXBTZ-CB[8] and the CD44-targeting feature of CSA, the formulated DXBTZ-CB[8]/CSA can effectively detect and diagnose subcutaneous tumors, orthotopic bladder tumors, lymphatic metastasis of tumors and ischemia/reperfusion-induced acute kidney injury in mouse models with multispectral optoacoustic imaging.
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