Evidence map›Paper›PMID 37400235›Full record

ArticleBMJ open2023

The eliminate hepatitis C (EC) experience study: baseline characteristics of a cohort of people who inject drugs in Melbourne, Australia.

Jack Gunn, Daniel O'Keefe, Bridget Louise Draper, Filip Djordjevic, Kathleen Ryan, Phoebe Kerr, Imogen Elsum, Judy Gold, Chloe Layton, Kico Chan and 6 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Jack GunnDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia jack.gunn@burnet.edu.au.ORCID 0000-0003-2867-6689
Daniel O'KeefeDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.ORCID 0000-0001-6799-2372
Bridget Louise DraperDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.ORCID 0000-0003-2624-2510
Filip DjordjevicDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Kathleen RyanDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Phoebe KerrDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Imogen ElsumDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Judy GoldDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.ORCID 0000-0002-3624-8900
Chloe LaytonDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Kico ChanDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Paul DietzeSchool of Public Health and Preventive Medicine, Monash University, Clayton, Victoria, Australia.
Peter HiggsBehaviours and Health Risks Program, Burnet Institute, Melbourne, Victoria, Australia.
Joseph DoyleDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Mark A StoovéDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Margaret HellardDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Alisa PedranaDisease Elimination Program, Burnet Institute, Melbourne, Victoria, Australia.
Burnet Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDirect-acting antivirals provide an opportunity to eliminate hepatitis C virus (HCV) as a public health threat in Australia, yet barriers to care remain. In this study, we use baseline data from a longitudinal cohort of people who inject drugs to understand differences in participant characteristics and explore experiences of stigma, health service utilisation and health literacy between three care cascade groups.

designCross-sectional.

settingCommunity and private primary healthcare services in Melbourne, Australia.

participantsParticipants completed baseline surveys between 19 September 2018 and 15 December 2020. We recruited 288 participants; the median age was 42 years (IQR: 37-49 years) and 198 (69%) were male. At baseline, 103 (36%) self-reported being 'not engaged in testing', 127 (44%) had HCV RNA positivity but were 'not engaged in treatment' and 58 (20%) were 'engaged in HCV treatment'. OUTCOME MEASURES: Descriptive statistics were used to present the baseline demographics, health service utilisation and experiences of stigma data. We explored differences in these scales between participant demographics using χ

resultsA majority were in regular contact with multiple health services, and most had previously been identified as at-risk of HCV. In the 12 months preceding baseline, 70% reported any experiences of stigma related to injecting drug use. Assessment of health literacy data identified gaps for those 'not engaged in testing' and 'not engaged in treatment' across two relevant domains: 'ability to appraise health information' and 'ability to actively engage with healthcare providers'.

conclusionIn eliminate hepatitis C experience, lower HCV testing and treatment may be explained by experiences of stigmatisation or gaps in health literacy. Enhanced interventions targeting people who inject drugs to promote HCV care are needed.

Indexed as

Drug UsersHepatitis CHepatitis C, ChronicSubstance Abuse, IntravenousAdultAntiviral AgentsAustraliaCross-Sectional StudiesFemaleHepacivirusHumansMaleAntiviral AgentsHealth policyHealth Services AccessibilityPublic health

Identifiers

PMID37400235
PMCPMC10335404
OpenAlexW4382931049

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.