Evidence map›Paper›PMID 37399433›Full record

ArticleBMJ open gastroenterology2023

EUS-guided through the needle microbiopsy: a useful adjunct in the investigation of pancreatic cystic lesions.

Wafaa Ahmed, Mikaeil Mirzaali, Caroline Young, Latifu Sanni, Simon Everett, Bharat Paranandi, Matthew T Huggett, Wei On

Abstract read
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Article in BMJ open gastroenterology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Wafaa AhmedDepartment of Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, UK wafaa.ahmed@nhs.net.ORCID 0000-0003-4034-7570
Mikaeil MirzaaliDepartment of Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Caroline YoungDepartment of Histopathology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Latifu SanniDepartment of Histopathology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Simon EverettDepartment of Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.ORCID 0000-0002-4251-5323
Bharat ParanandiDepartment of Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Matthew T HuggettDepartment of Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Wei OnDepartment of Gastroenterology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.ORCID 0000-0002-9672-282X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEndoscopic ultrasound-guided through-the-needle microbiopsy (EUS-TTNB) forceps is a recent development that facilitates sampling of the walls of pancreatic cystic lesions (PCL) for histological analysis. We aimed to assess the impact of EUS-TTNB and its influence on patient management in a tertiary pancreas centre.

designA prospective database of consecutive patients who underwent EUS-TTNB from March 2020 to August 2022 at a tertiary referral centre was retrospectively analysed.

resultsThirty-four patients (22 women) were identified. Technical success was achieved in all cases. Adequate specimens for histological diagnosis were obtained in 25 (74%) cases. Overall, EUS-TTNB led to a change in management in 24 (71%) cases. Sixteen (47%) patients were downstaged, with 5 (15%) discharged from surveillance. Eight (24%) were upstaged, with 5 (15%) referred for surgical resection. In the 10 (29%) cases without change in management, 7 (21%) had confirmation of diagnosis with no change in surveillance, and 3 (9%) had insufficient biopsies on EUS-TTNB. Two (6%) patients developed post-procedural pancreatitis, and 1 (3%) developed peri-procedural intracystic bleeding with no subsequent clinical sequelae.

conclusionEUS-TTNB permits histological confirmation of the nature of PCL, which can alter management outcomes. Care should be taken in patient selection and appropriately consented due to the adverse event rate.

Indexed as

Endoscopic Ultrasound-Guided Fine Needle AspirationPancreatic CystEndosonographyFemaleHumansPancreasRetrospective Studiesdisease stagingEUSIPMNpancreatic cystic lesionsthrough the needle microbiopsy

Identifiers

PMID37399433
PMCPMC10314575

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