Evidence map›Paper›PMID 37399408›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Phase separation and molecular ordering of the prion-like domain of the Arabidopsis thermosensory protein EARLY FLOWERING 3.

Stephanie Hutin, Janet R Kumita, Vivien I Strotmann, Anika Dolata, Wai Li Ling, Nessim Louafi, Anton Popov, Pierre-Emmanuel Milhiet, Martin Blackledge, Max H Nanao and 5 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Principles and mechanisms of plant acclimation to heat stress.Nature reviews. Molecular cell biology · 2026
    Review
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  5. Current Challenges of Transcription Compartmentalization Research.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
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  7. Article
  8. Review
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  17. Article
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  19. Article
  20. Mechanisms and Pathological Significance of Liquid-Liquid Phase Separation in Bacteria.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 3 countries.

Stephanie HutinLaboratoire de Physiologie Cellulaire et Végétale, University Grenoble Alpes, Centre national de la recherche scientifique, Commissariat à l'énergie atomique et aux énergies alternatives, Institut national de recherche pour l'agriculture, l'alimentation et l'environnement, Institut de recherche interdisciplinaire de Grenoble, Grenoble 38054, France.ORCID 0000-0002-2168-5841
Janet R KumitaDepartment of Pharmacology, University of Cambridge, Cambridge CB2 1PD, United Kingdom.
Vivien I StrotmannInstitute for Developmental Genetics, Heinrich-Heine University, Düsseldorf D-40225, Germany.ORCID 0000-0003-4822-6706
Anika DolataInstitute for Developmental Genetics, Heinrich-Heine University, Düsseldorf D-40225, Germany.ORCID 0000-0003-2481-3113
Wai Li LingUniversity Grenoble Alpes, Commissariat à l'énergie atomique et aux énergies alternatives, Centre national de la recherche scientifique, Institut de Biologie Structurale, Institut de recherche interdisciplinaire de Grenoble, Grenoble 38000, France.ORCID 0000-0002-4264-5750
Nessim LouafiCentre de Biologie Structurale, University Montpellier, Centre national de la recherche scientifique, Institut national de la santé et de la recherche médicale, Montpellier 34090, France.
Anton PopovEuropean Synchrotron Radiation Facility, Structural Biology Group, Grenoble 38000, France.ORCID 0000-0003-3371-3552
Pierre-Emmanuel MilhietCentre de Biologie Structurale, University Montpellier, Centre national de la recherche scientifique, Institut national de la santé et de la recherche médicale, Montpellier 34090, France.ORCID 0000-0002-0410-5956
Martin BlackledgeUniversity Grenoble Alpes, Commissariat à l'énergie atomique et aux énergies alternatives, Centre national de la recherche scientifique, Institut de Biologie Structurale, Institut de recherche interdisciplinaire de Grenoble, Grenoble 38000, France.
Max H NanaoEuropean Synchrotron Radiation Facility, Structural Biology Group, Grenoble 38000, France.
Philip A WiggeLeibniz-Institut für Gemüse- und Zierpflanzenbau, 14979 Grossbeeren, Germany.ORCID 0000-0003-4822-361X
Yvonne StahlInstitute for Developmental Genetics, Heinrich-Heine University, Düsseldorf D-40225, Germany.
Luca CostaCentre de Biologie Structurale, University Montpellier, Centre national de la recherche scientifique, Institut national de la santé et de la recherche médicale, Montpellier 34090, France.ORCID 0000-0002-4527-0034
Mark D TullyEuropean Synchrotron Radiation Facility, Structural Biology Group, Grenoble 38000, France.ORCID 0000-0001-5450-9900
Chloe ZubietaLaboratoire de Physiologie Cellulaire et Végétale, University Grenoble Alpes, Centre national de la recherche scientifique, Commissariat à l'énergie atomique et aux énergies alternatives, Institut national de recherche pour l'agriculture, l'alimentation et l'environnement, Institut de recherche interdisciplinaire de Grenoble, Grenoble 38054, France.ORCID 0000-0003-4558-9333
Commissariat à l'Énergie Atomique et aux Énergies Alternatives · FRCentre de Biologie Structurale · FREuropean Synchrotron Radiation Facility · FRHeinrich Heine University Düsseldorf · DECluster of Excellence on Plant Sciences · DEUniversity of Cambridge · GBUniversity of Potsdam · DE

Funding

Medical Research Council MR/W01632X/1
6 · The paper itself

Abstract

Liquid-liquid phase separation (LLPS) is an important mechanism enabling the dynamic compartmentalization of macromolecules, including complex polymers such as proteins and nucleic acids, and occurs as a function of the physicochemical environment. In the model plant,

Indexed as

ArabidopsisArabidopsis ProteinsTranscription FactorsPrionsTemperatureArabidopsis ProteinsAt2g25930 protein, ArabidopsisPrionsTranscription Factorsatomic force microscopyEARLY FLOWERING 3phase separationsmall angle X-ray scatteringthermosensing

Identifiers

PMID37399408
PMCPMC10334799
OpenAlexW4382930913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.