Evidence map›Paper›PMID 37399371›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Qualitative metabolomics-based characterization of a phenolic UDP-xylosyltransferase with a broad substrate spectrum from

Eunah Jeong, Wonyong Kim, Seungju Son, Sungyeon Yang, Dasom Gwon, Jihee Hong, Yoonhee Cho, Chang-Young Jang, Martin Steinegger, Young Woon Lim and 1 more

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Eunah JeongCollege of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.ORCID 0009-0008-0437-9210
Wonyong KimKorean Lichen Research Institute, Sunchon National University, Suncheon 57922, Korea.ORCID 0000-0002-9094-8908
Seungju SonCollege of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.
Sungyeon YangCollege of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.ORCID 0000-0002-5033-6181
Dasom GwonCollege of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.
Jihee HongCollege of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.ORCID 0000-0002-1981-3760
Yoonhee ChoSchool of Biological Sciences, Seoul National University, Seoul 08826, Korea.
Chang-Young JangCollege of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.ORCID 0000-0003-1177-3239
Martin SteineggerSchool of Biological Sciences, Seoul National University, Seoul 08826, Korea.ORCID 0000-0001-8781-9753
Young Woon LimSchool of Biological Sciences, Seoul National University, Seoul 08826, Korea.
Kyo Bin KangCollege of Pharmacy, Sookmyung Women's University, Seoul 04310, Korea.ORCID 0000-0003-3290-1017
Sookmyung Women's University · KRSeoul National University · KRSunchon National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wood-decaying fungi are the major decomposers of plant litter. Heavy sequencing efforts on genomes of wood-decaying fungi have recently been made due to the interest in their lignocellulolytic enzymes; however, most parts of their proteomes remain uncharted. We hypothesized that wood-decaying fungi would possess promiscuous enzymes for detoxifying antifungal phytochemicals remaining in the dead plant bodies, which can be useful biocatalysts. We designed a computational mass spectrometry-based untargeted metabolomics pipeline for the phenotyping of biotransformation and applied it to 264 fungal cultures supplemented with antifungal plant phenolics. The analysis identified the occurrence of diverse reactivities by the tested fungal species. Among those, we focused on

Indexed as

GlucosyltransferasesLentinulaMetabolomicsGenome, FungalLiquid Chromatography-Mass SpectrometryPhytochemicalsXyloseGlucosyltransferasesPhytochemicalsXylosebiocatalystmetabolomicssubstrate promiscuityUDP-glycosyltransferasewood-decaying fungi

Identifiers

PMID37399371
PMCPMC10334773
OpenAlexW4382932151

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.