Evidence map›Paper›PMID 37399331›Full record

ArticleGenes & development2023

Nuclear mRNPs are compact particles packaged with a network of proteins promoting RNA-RNA interactions.

Fabien Bonneau, Jérôme Basquin, Barbara Steigenberger, Tillman Schäfer, Ingmar B Schäfer, Elena Conti

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 40 citations in OpenAlex.

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  15. Structures and mRNP remodeling mechanism of the TREX-2 complex.Structure (London, England : 1993) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Fabien BonneauDepartment of Structural Cell Biology, Max Planck Institute of Biochemistry, Martinsried/Munich D-82152, Germany.ORCID 0000-0001-8787-7662
Jérôme BasquinDepartment of Structural Cell Biology, Max Planck Institute of Biochemistry, Martinsried/Munich D-82152, Germany.
Barbara SteigenbergerMass Spectrometry Core Facility, Max Planck Institute of Biochemistry, Martinsried/Munich D-82152, Germany.ORCID 0000-0002-5244-1903
Tillman SchäferElectron Microscopy Core Facility, Max Planck Institute of Biochemistry, Martinsried/Munich D-82152, Germany.
Ingmar B SchäferDepartment of Structural Cell Biology, Max Planck Institute of Biochemistry, Martinsried/Munich D-82152, Germany.ORCID 0000-0002-7301-7300
Elena ContiDepartment of Structural Cell Biology, Max Planck Institute of Biochemistry, Martinsried/Munich D-82152, Germany; conti@biochem.mpg.de.ORCID 0000-0003-1254-5588
Max Planck Institute of Biochemistry · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Messenger RNAs (mRNAs) are at the center of the central dogma of molecular biology. In eukaryotic cells, these long ribonucleic acid polymers do not exist as naked transcripts; rather, they associate with mRNA-binding proteins to form messenger ribonucleoprotein (mRNP) complexes. Recently, global proteomic and transcriptomic studies have provided comprehensive inventories of mRNP components. However, knowledge of the molecular features of distinct mRNP populations has remained elusive. We purified endogenous nuclear mRNPs from

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCryoelectron MicroscopyProteomicsRibonucleoproteinsRNARNA-Binding ProteinsRNA, Messengermessenger ribonucleoproteinRibonucleoproteinsRNARNA-Binding ProteinsRNA, MessengerSaccharomyces cerevisiae ProteinsCHTOPcross-linking mass spectrometry (XL-MS)cryo-electron tomography (cryo-ET)EJCERHIDRribonucleoprotein particlesRNA annealingSub2THOTREXUAP56

Identifiers

PMID37399331
PMCPMC10393194
OpenAlexW4382931278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.