Evidence map›Paper›PMID 37399082›Full record

SynthesisThe British journal of radiology2023

Interobserver variability studies in diagnostic imaging: a methodological systematic review.

Laura Quinn, Konstantinos Tryposkiadis, Jon Deeks, Henrica C W De Vet, Sue Mallett, Lidwine B Mokkink, Yemisi Takwoingi, Sian Taylor-Phillips, Alice Sitch

Abstract readSystematic Review
In one paragraph

Synthesis in The British journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Computed Tomographic Lesion Descriptors in Foals With Hematogenous Osteomyelitis: Interobserver Agreement and Association With Outcome.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026
    Article
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  8. Machine Learning-Based Cytokine Endotyping of Thyroid Eye Disease.Investigative ophthalmology & visual science · 2026
    Article
  9. Article
  10. Clinical and MRI factors influencing interobserver delineation variability of brain metastases before stereotactic radiotherapy.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
    Article
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  12. Review
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  19. Point-of-Care Ultrasound in Airway Management.Journal of clinical medicine · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Laura QuinnTest Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.ORCID 0000-0001-9660-4631
Konstantinos TryposkiadisTest Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Jon DeeksTest Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Henrica C W De VetDepartment of Epidemiology and Data Science, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Sue MallettCentre for Medical Imaging, University College London, London, United Kingdom.
Lidwine B MokkinkDepartment of Epidemiology and Data Science, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Yemisi TakwoingiTest Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Sian Taylor-PhillipsTest Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.
Alice SitchTest Evaluation Research Group, Institute of Applied Health Research, University of Birmingham, Birmingham, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo review the methodology of interobserver variability studies; including current practice and quality of conducting and reporting studies.

methodsInterobserver variability studies between January 2019 and January 2020 were included; extracted data comprised of study characteristics, populations, variability measures, key results, and conclusions. Risk of bias was assessed using the COSMIN tool for assessing reliability and measurement error.

resultsSeventy-nine full-text studies were included covering various imaging tests and clinical areas. The median number of patients was 47 (IQR:23-88), and observers were 4 (IQR:2-7), with sample size justified in 12 (15%) studies. Most studies used static images (

conclusionsInterobserver variability studies have diverse study designs and methods, the impact of which requires further evaluation. Sample size for patients and observers was often small without justification. Most studies report ICC and κ values, which did not always coincide with the study conclusion. High ratings were assigned to many studies using the COSMIN risk of bias tool, with certain standards scored 'not applicable' when static images were used. ADVANCES IN KNOWLEDGE: The sample size for both patients and observers was often small without justification. For most studies, observers interpreted static images and did not evaluate the process of acquiring the imaging test, meaning it was not possible to assess many COSMIN risk of bias standards for studies with this design. Most studies reported intraclass correlation coefficient and κ statistics; study conclusions often did not correspond with results.

Indexed as

Diagnostic ImagingResearch DesignHumansObserver VariationReproducibility of Results

Identifiers

PMID37399082
PMCPMC10392644

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.