Evidence map›Paper›PMID 37398707›Full record

ArticleCureus2023

Exploring the Correlates of Hematological Parameters With Early Diabetic Nephropathy in Type 2 Diabetes Mellitus.

Susmitha Chollangi, Nikunj K Rout, Sudhir K Satpathy, Bandita Panda, Shubhransu Patro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Comparison of complete blood count parameters in different severity of proteinuria among patients with type 2 diabetes mellitus.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Susmitha ChollangiDepartment of General Medicine, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology Deemed to be University, Bhubaneswar, IND.
Nikunj K RoutDepartment of Nephrology, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology Deemed to be University, Bhubaneswar, IND.
Sudhir K SatpathyDepartment of General Medicine, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology Deemed to be University, Bhubaneswar, IND.
Bandita PandaDepartment of Research and Development, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology Deemed to be University, Bhubaneswar, IND.
Shubhransu PatroDepartment of General Medicine, Kalinga Institute of Medical Sciences, Kalinga Institute of Industrial Technology Deemed to be University, Bhubaneswar, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 2 diabetes mellitus (DM) with nephropathy is a common complication in poorly controlled diabetes. Uncontrolled DM leads to intraglomerular vascular changes that cause physical injury to capillary walls, causing a profibrotic response in kidneys. The present study aimed to determine the association of hematological markers with microalbuminuria in early diabetic nephropathy.

methodsA single-center, cross-sectional study was conducted over the period of two years at the Department of Medicine of Pradyumna Bal Memorial Hospital, Kalinga Institute of Medical Sciences. A total of 90 patients diagnosed with type 2 DM were classified into two groups (group A and group B) according to microalbuminuria; there were 45 patients in each group. Levels of hematological markers, i.e., neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width (RDW), between the study groups were examined and compared.

resultsA significant difference in NLR was found between groups A and B (p = 0.001). A statistically significant difference in RDW was found between the groups (p = 0.015). Receiver operating characteristic curve analysis of inflammatory markers and microalbuminuria prediction showed an area under the curve of 0.814 for NLR and 0.656 for RDW.

conclusionHematological parameters like NLR and RDW are elevated in early diabetic nephropathy patients. NLR is found to be a better marker than RDW in predicting early nephropathy.

Indexed as

diabetic nephropathymicroalbuminurianeutrophil to lymphocyte ratio (nlr)red blood cell distribution (rdw)red cell distribution widthtype 2 diabetestype 2 diabetes mellitus

Identifiers

PMID37398707
PMCPMC10312475

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.