ReviewFrontiers in immunology2023
Immune functions of pattern recognition receptors in Lepidoptera.
Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 40 citations in OpenAlex.
- Role of Pattern Recognition Receptors (PRRs) in Spinal Cord Injury (SCI): A Comprehensive Review.Molecular neurobiology · 2026Review
- Non-Coding Transcripts From Diversified Members of IgLec Family Protect Antiviral Effectors From Viral miRNA.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- RfGNBP5 Negatively Regulates Innate Immunity of Red Palm Weevil,Microorganisms · 2026Article
- In silico discovery and mechanistic profiling of STING agonists engaging the transmembrane domain.European journal of medicinal chemistry · 2026Article
- Both lipopolysaccharide and vehicle treatments upregulate complement-dependent and complement-independent innate immune responses in Diamond-backed Watersnakes (Squamata:Frontiers in immunology · 2026Article
- Disruption ofVirulence · 2025Article
- Chemosensory protein 16 has an immune function and participates in host-pathogen interaction inVirulence · 2025Article
- Pathogens That Rewrite the Rules: Ascoviruses, Elegant Manipulators of Cell Death Pathways and Architects of the Extracellular Viral Paradigm.Pathogens (Basel, Switzerland) · 2025Review
- Human Microbiome as an Immunoregulatory Axis: Mechanisms, Dysbiosis, and Therapeutic Modulation.Microorganisms · 2025Review
- Staphylococcus aureus biofilm-associated component PNAG stimulates the secretion of the immunomodulatory chemokine CXCL10 via Dectin-1 signaling.Communications biology · 2025Article
- Article
- Structure, Function, and Regulation of LytA: TheMicroorganisms · 2025Review
- Immune-Related Genes in the Honey Bee MiteInsects · 2025Article
- Innate Immunity in Insects: The Lights and Shadows of Phenoloxidase System Activation.International journal of molecular sciences · 2025Review
- Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos.PloS one · 2025Article
- Review
- Comparative Analysis of PGRP Family in Polymorphic Worker Castes ofInternational journal of molecular sciences · 2024Article
- Identification and functional analysis of C-type lectin from mosquito Aedes albopictus in response to dengue virus infection.Parasites & vectors · 2024Article
- Immune Gene Repertoire of Soft Scale Insects (Hemiptera: Coccidae).International journal of molecular sciences · 2024Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pattern recognition receptors (PRRs), as the "sensors" in the immune response, play a prominent role in recognizing pathogen-associated molecular patterns (PAMPs) and initiating an effective defense response to pathogens in Lepidoptera. It is becoming increasingly clear that damage-associated molecular patterns (DAMPs) normally play a physiological role within cells; however, when exposed to extracellular, they may become "part-time" critical signals of the immune response. Based on research in recent years, we review herein typical PRRs of Lepidoptera, including peptidoglycan recognition protein (PGRP), gram-negative binding protein (GNBP), β-1,3-glucan recognition protein (βGRP), C-type lectin (CTL), and scavenger receptor (SR). We also outline the ways in which DAMPs participate in the immune response and the correlation between PRRs and immune escape. Taken together, these findings suggest that the role of PRRs in insect innate immunity may be much greater than expected and that it is possible to recognize a broader range of signaling molecules.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.