Evidence map›Paper›PMID 37398607›Full record

ArticleF&S reports2023

Birth of monozygotic dichorionic twins after a single blastocyst embryo transfer: a case report of genetic determination of zygosity.

Neli Semrl, Michael Barth, Sarah Feigl, Rüdiger Hochstätter, Irmgard Oreskovic, Herbert Fluhr, Philipp Klaritsch, Irene Speicher, Martina Kollmann

Abstract read
In one paragraph

Article in F&S reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Neli SemrlDepartment of Obstetrics and Gynecology, Medical University of Graz, Austria.
Michael BarthDepartment of Obstetrics and Gynecology, Medical University of Graz, Austria.
Sarah FeiglDepartment of Obstetrics and Gynecology, Medical University of Graz, Austria.
Rüdiger HochstätterDepartment of Obstetrics and Gynecology, Medical University of Graz, Austria.
Irmgard OreskovicDepartment of Obstetrics and Gynecology, Medical University of Graz, Austria.
Herbert FluhrDepartment of Obstetrics and Gynecology, Medical University of Graz, Austria.
Philipp KlaritschDepartment of Obstetrics and Gynecology, Medical University of Graz, Austria.
Irene SpeicherThe Diagnostic and Research Institute of Pathology, Medical University of Graz, Austria.
Martina KollmannDepartment of Obstetrics and Gynecology, Medical University of Graz, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To report a case of monozygotic dichorionic (DC) twins after a single cryopreserved blastocyst embryo transfer followed by genetic determination of zygosity postpartum. Design: Case report. Setting: University hospital. Patients: A 26-year-old woman with polycystic ovary syndrome and her 36-year-old male partner with severe oligozoospermia, resulting in a 1.5-year history of primary infertility. Interventions: Controlled ovarian stimulation and intracytoplasmic sperm injection treatment with single cryopreserved embryo transfer at blastocyst stage. Main Outcome Measures: Ultrasound images of the fetuses and short tandem repeat genotyping postpartum. Results: A DC twin pregnancy following a single cryopreserved blastocyst embryo transfer was confirmed at the first trimester screening. Confirmatory testing performed postpartum included short tandem repeat analysis determining monozygosity and pathology examination reporting DC placental configuration. Conclusions: Dichorionic monozygotic twins are thought to arise from the splitting of an embryo before the blastocyst stage. This case suggests that placental configuration of monozygotic twins may not strictly depend on timing of embryo division. Genetic analysis is the only tool to confirm the zygosity.

Indexed as

DNA analysisICSImonozygotic dichorionic twinssingle blastocyst embryo transfer

Identifiers

PMID37398607
PMCPMC10310970

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