ArticleFrontiers in psychiatry2023
Gender specific sexual dysfunction in patients with depression.
Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pharmacological treatment of antidepressant-induced sexual dysfunction in women: A systematic review and meta-analysis of randomized clinical trials.Clinics (Sao Paulo, Brazil) · 2025Pooled it
- Effect of l-arginine compared to placebo on sexual function in women with major depressive disorder: a randomized controlled trial.BMC psychiatry · 2024Trial
- Sexual dysfunction and distress in patients with depressive disorders at a tertiary care hospital in Riyadh, Saudi Arabia: a cross-sectional study.BMC psychiatry · 2026Article
- Differentiation between depressive disorder and insomnia disorder with depressive symptoms across age groups using machine learning.Frontiers in psychiatry · 2026Article
- Sexual Dysfunction in Traumatic Brain Injury: A Narrative Review and Call for Multidisciplinary Framework.Life (Basel, Switzerland) · 2025Review
- Association of Sexual Dysfunction, Vitamin D, and Thyroid Levels with Suicidal Behavior Among Patients with Depressive Disorder: A Cross-sectional Study.Indian journal of psychological medicine · 2025Article
- The complex relationships among self-acceptance, perceived social support, drug use stereotype threat, and subthreshold depression in people with substance use disorder: exploring the mediating and buffering effects.Frontiers in psychiatry · 2025Article
- An interdisciplinary intervention for detection of sexual dysfunction associated with antidepressants: A pilot study.The mental health clinician · 2024Article
- Sexual Dysfunction Induced by Antidepressants-A Pharmacovigilance Study Using Data from VigiBasePharmaceuticals (Basel, Switzerland) · 2024Article
- Prevalence of sexual dysfunction and its association with psychological symptoms in drug-naive major depressive disorder patients in West China.Frontiers in psychiatry · 2023Article
- Using network analysis to model associations between psychological symptoms, sexual function, and sexual distress in women.International journal of clinical and health psychology : IJCHPArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aims to investigate the factors associated with sexual dysfunction (SD), with a particular focus on the influence of sex on the occurrence and severity of this condition in patients with major depressive disorder (MDD). Method: Sociodemographic and clinical assessments were conducted on 273 patients with MDD (female = 174, male = 99), including the ASEX, QIDS-SR16, GAD-7, and PHQ-15. Univariate analyses, independent samples Result: SD was reported in 61.9% of the participants (ASEX score = 19.6 ± 5.5), and the prevalence of it in females (75.3%, ASEX score = 21.1 ± 5.4) was significantly higher than that in males (38.4%, ASEX score = 17.1 ± 4.6). Factors associated with SD included being female, being aged 45 years or above, having a low monthly income (≤750 USD), feeling more sluggish than usual (a QIDS-SR16 Item 15 score of 1 or above), and having somatic symptoms (evaluated with the total score of PHQ15). Limitation: The use of antidepressants and antipsychotics might be a confounding factor affecting sexual function. Also, the lack of information in the clinical data regarding the number, duration, and time of onset of the episodes limits the richness of the results. Conclusion: Our findings reveal the sex differences in the prevalence and severity of SD in patients with MDD. Evaluated with the ASEX score, female patients showed significantly worse sexual function than male patients. Being female, having a low monthly income, being aged 45 years or above, feeling sluggish, and having somatic symptoms may increase the risk of SD in patients with MDD.
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