Evidence map›Paper›PMID 37398383›Full record

ArticlebioRxiv : the preprint server for biology2023

"Evolution of the mutation spectrum across a mammalian phylogeny".

Annabel C Beichman, Jacqueline Robinson, Meixi Lin, Andrés Moreno-Estrada, Sergio Nigenda-Morales, Kelley Harris

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Annabel C BeichmanDepartment of Genome Sciences, University of Washington, Seattle WA.
Jacqueline RobinsonInstitute for Human Genetics, University of California, San Francisco, San Francisco, CA.
Meixi LinDepartment of Plant Biology, Carnegie Institution for Science, Stanford, CA.
Andrés Moreno-EstradaNational Laboratory of Genomics for Biodiversity, Advanced Genomics Unit (UGA-LANGEBIO), CINVESTAV, Irapuato, Mexico.
Sergio Nigenda-MoralesDepartment of Biological Sciences, California State University, San Marcos, San Marcos CA.
Kelley HarrisDepartment of Genome Sciences, University of Washington, Seattle WA.

Funding

Biological Mechanisms of Healthy Aging Training GrantT32AG066574 · NIA · UNIVERSITY OF WASHINGTON · PI David J. Marcinek, Jessica E Young · 2020 to 2026
$5.3M
Investigating the landscape and genetic architecture of germline mutagenesisR35GM133428 · NIGMS · UNIVERSITY OF WASHINGTON · PI Kelley Harris · 2019 to 2026
$2.8M
NIA NIH HHS T32 AG066574NIGMS NIH HHS R35 GM133428
6 · The paper itself

Abstract

Little is known about how the spectrum and etiology of germline mutagenesis might vary among mammalian species. To shed light on this mystery, we quantify variation in mutational sequence context biases using polymorphism data from thirteen species of mice, apes, bears, wolves, and cetaceans. After normalizing the mutation spectrum for reference genome accessibility and

Identifiers

PMID37398383
PMCPMC10312511

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.