Evidence map›Paper›PMID 37398377›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Variants in the SOX9 transactivation middle domain induce axial skeleton dysplasia and scoliosis.

Lianlei Wang, Zhaoyang Liu, Sen Zhao, Kexin Xu, Valeria Aceves, Cheng Qiu, Benjamin Troutwine, Lian Liu, Samuel Ma, Yuchen Niu and 9 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Lianlei Wang
Zhaoyang Liu
Sen Zhao
Kexin Xu
Valeria Aceves
Cheng Qiu
Benjamin Troutwine
Lian Liu
Samuel Ma
Yuchen Niu
Shengru Wang
Suomao Yuan
Xiaoxin Li
Lina Zhao
Xinyu Liu
Zhihong Wu
Terry Jianguo Zhang
Ryan S Gray
Nan Wu

Funding

Analyzing the role of cAMP and STAT3 signaling in cartilage homeostasis and osteoarthritis developmentR00AR077090 · NIAMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LIU, ZHAOYANG · 2023 to 2025
$686k
NIAMS NIH HHS R00 AR077090
6 · The paper itself

Abstract

SOX9 is an essential transcriptional regulator of cartilage development and homeostasis. In humans, dysregulation of

Identifiers

PMID37398377
PMCPMC10312849

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.