Evidence map›Paper›PMID 37398330›Full record

ArticlebioRxiv : the preprint server for biology2023

BRI2-mediated regulation of TREM2 processing in microglia and its potential implications for Alzheimer's disease and related dementias.

Tao Yin, Luciano D'Adamio

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tao YinDepartment of Pharmacology, Physiology & Neuroscience New Jersey Medical School, Brain Health Institute, Jacqueline Krieger Klein Center in Alzheimer's Disease and Neurodegeneration Research, Rutgers, The State University of New Jersey, 205 South Orange Ave, Newark, NJ, 07103, USA.
Luciano D'AdamioDepartment of Pharmacology, Physiology & Neuroscience New Jersey Medical School, Brain Health Institute, Jacqueline Krieger Klein Center in Alzheimer's Disease and Neurodegeneration Research, Rutgers, The State University of New Jersey, 205 South Orange Ave, Newark, NJ, 07103, USA.
Rutgers, The State University of New Jersey · US

Funding

BRI2 Familial British and Danish Dementias and Alzheimer's DiseaseR01AG033007 · NIA · RBHS-NEW JERSEY MEDICAL SCHOOL · PI D'ADAMIO, LUCIANO · 2009 to 2019
$4.2M
Studies of dementia pathogenesis in genetically faithful rat models of Familal Alzheimer diseaseR01AG063407 · NIA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI D'ADAMIO, LUCIANO · 2019 to 2023
$3.9M
Are mechanisms leading to FAD, SAD and age-associated cognitive decline similar?RF1AG064821 · NIA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI D'ADAMIO, LUCIANO · 2019 to 2019
$3.9M
Trem2-mediated microglia-neuronal axis in Alzheimer disease pathogenesisR01AG073182 · NIA · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI D'ADAMIO, LUCIANO · 2021 to 2025
$3.9M
Novel Animal Models of Familial British, Danish and Alzheimer's DementiaR21AG027139 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI D'ADAMIO, LUCIANO · 2006 to 2007
$382k
NIA NIH HHS R01 AG033007NIA NIH HHS R01 AG063407NIA NIH HHS R01 AG073182NIA NIH HHS R21 AG027139NIA NIH HHS RF1 AG064821
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alzheimer diseaseAlzheimer disease-related dementiaBRI2microglianeurodegenerationneuroinflammationTrem2α-secretase

Identifiers

PMID37398330
PMCPMC10312752
OpenAlexW4380550400

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.