Evidence map›Paper›PMID 37398284›Full record

ArticlebioRxiv : the preprint server for biology2023

CRISPR-based gene drives generate super-Mendelian inheritance in the disease vector

Tim Harvey-Samuel, Xuechun Feng, Emily M Okamoto, Deepak-Kumar Purusothaman, Philip T Leftwich, Luke Alphey, Valentino M Gantz

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Tim Harvey-SamuelArthropod Genetics Group, The Pirbright Institute, Woking, UK, GU24 0NF.
Xuechun FengSection of Cell and Developmental Biology, University of California San Diego, La Jolla, CA, USA 92093.
Emily M OkamotoSection of Cell and Developmental Biology, University of California San Diego, La Jolla, CA, USA 92093.
Deepak-Kumar PurusothamanArthropod Genetics Group, The Pirbright Institute, Woking, UK, GU24 0NF.
Philip T LeftwichSchool of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich, UK, NR4 7TJ.
Luke AlpheyPresent address: Biology Department, University of York, York, UK, YO10 5DD.
Valentino M GantzSection of Cell and Developmental Biology, University of California San Diego, La Jolla, CA, USA 92093.
University of California San Diego · USThe Pirbright Institute · GBUniversity of East Anglia · GBUniversity of York · GB

Funding

Development of next-generation gene drive technologies for Anopheles population engineeringR01AI162911 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BIER, ETHAN · 2021 to 2025
$2.3M
Development, characterization and application of CRISPR/Cas9 gene drive technologies and related active genetic elements to benefit research and society at largeDP5OD023098 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GANTZ, VALENTINO MATTEO · 2016 to 2020
$1.9M
Biotechnology and Biological Sciences Research Council BBS/E/I/00007039NIAID NIH HHS R01 AI162911NIH HHS DP5 OD023098
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID37398284
PMCPMC10312623
OpenAlexW4380680100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.