Evidence map›Paper›PMID 37398194›Full record

ArticleResearch square2023

Proposal of a new genomic framework for categorization of pediatric acute myeloid leukemia associated with prognosis.

Masayuki Umeda, Jing Ma, Tamara Westover, Yonghui Ni, Guangchun Song, Jamie L Maciaszek, Michael Rusch, Delaram Rahbarinia, Scott Foy, Benjamin J Huang and 11 more

Open access · greenAbstract readPreprint
In one paragraph

Article in Research square, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 3 institutions in 2 countries.

Masayuki UmedaDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jing MaDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Tamara WestoverDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-1000-6698
Yonghui NiDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.
Guangchun SongDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jamie L MaciaszekDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Michael RuschDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-5363-1848
Delaram RahbariniaDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Scott FoyDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Benjamin J HuangDepartment of Pediatrics, University of California San Francisco, San Francisco, CA, US.ORCID 0000-0001-6996-0833
Michael P WalshDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Priyadarshini KumarDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Yanling LiuDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Yiping FanCenter for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN, USA.
Gang WuDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-1678-5864
Sharyn D BakerDivision of Pharmaceutics and Pharmacology, College of Pharmacy, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA.
Xiaotu MaDepartment of Computational Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-6233-2145
Lu WangDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jeffrey E RubnitzDepartment of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0001-9885-3527
Stanley PoundsDepartment of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-9167-2114
Jeffery M KlcoDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0003-2961-6960
St. Jude Children's Research Hospital · USThe Ohio State University · USUniversity of California, San Francisco · US

Funding

Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Shondra Michelle Miller · 1985 to 2026
$166.9M
NCI NIH HHS P30 CA021765
6 · The paper itself

Abstract

Recent studies on pediatric acute myeloid leukemia (pAML) have revealed pediatric-specific driver alterations, many of which are underrepresented in the current classification schemas. To comprehensively define the genomic landscape of pAML, we systematically categorized 895 pAML into 23 molecular categories that are mutually distinct from one another, including new entities such as

Identifiers

PMID37398194
PMCPMC10312943
OpenAlexW4378611406

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.