Evidence map›Paper›PMID 37398067›Full record

ArticlebioRxiv : the preprint server for biology2023

De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity.

Rubul Mout, Ross C Bretherton, Justin Decarreau, Sangmin Lee, Natasha I Edman, Maggie Ahlrichs, Yang Hsia, Danny D Sahtoe, George Ueda, Nicole Gregorio and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Rubul MoutDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
Ross C BrethertonDepartment of Bioengineering, University of Washington, Seattle, WA 98195.
Justin DecarreauDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
Sangmin LeeDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
Natasha I EdmanDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
Maggie AhlrichsDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
Yang HsiaDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
Danny D SahtoeDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
George UedaDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
Nicole GregorioDepartment of Bioengineering, University of Washington, Seattle, WA 98195.
Alee SharmaStem Cell Program at Boston Children's Hospital, Harvard Medical School, Boston, MA 02115.
Rebecca SchulmanDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD 21218.
Cole A DeForestInstitute for Protein Design, University of Washington, Seattle, WA 98195.
David BakerDepartment of Biochemistry, University of Washington, Seattle, WA 98195.
University of Washington · USBoston Children's Hospital · USHoward Hughes Medical Institute · USJohns Hopkins University · US

Funding

Mimicking, Exploiting, and Understanding Biology's Heterogeneity in 4DR35GM138036 · NIGMS · UNIVERSITY OF WASHINGTON · PI Cole A DeForest · 2020 to 2026
$2.3M
NIGMS NIH HHS R35 GM138036
6 · The paper itself

Abstract

Relating the macroscopic properties of protein-based materials to their underlying component microstructure is an outstanding challenge. Here, we exploit computational design to specify the size, flexibility, and valency of

Identifiers

PMID37398067
PMCPMC10312586
OpenAlexW4379285192

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.