Evidence map›Paper›PMID 37398061›Full record

ArticlebioRxiv : the preprint server for biology2024

The Geometric Basis of Epithelial Convergent Extension.

Fridtjof Brauns, Nikolas H Claussen, Matthew F Lefebvre, Eric F Wieschaus, Boris I Shraiman

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 7 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fridtjof BraunsKavli Institute for Theoretical Physics, University of California Santa Barbara, Santa Barbara, California 93106, USA.ORCID 0000-0002-6108-9278
Nikolas H ClaussenDepartment of Physics, University of California Santa Barbara, Santa Barbara, California 93106, USA.ORCID 0000-0002-9020-6437
Matthew F LefebvreDepartment of Physics, University of California Santa Barbara, Santa Barbara, California 93106, USA.ORCID 0000-0002-9590-4293
Eric F WieschausDepartment of Molecular Biology, Princeton University, Princeton, NJ, USA; The Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-0727-3349
Boris I ShraimanKavli Institute for Theoretical Physics, University of California Santa Barbara, Santa Barbara, California 93106, USA.ORCID 0000-0003-0886-8990
University of California, Santa Barbara · USPrinceton University · US

Funding

Physics of Living Matter: From Molecule to Embryo.R35GM138203 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI Sebastian J Streichan · 2020 to 2026
$2.7M
NIGMS NIH HHS R35 GM138203
6 · The paper itself

Abstract

Shape changes of epithelia during animal development, such as convergent extension, are achieved through concerted mechanical activity of individual cells. While much is known about the corresponding large scale tissue flow and its genetic drivers, fundamental questions regarding local control of contractile activity on cellular scale and its embryo-scale coordination remain open. To address these questions, we develop a quantitative, model-based analysis framework to relate cell geometry to local tension in recently obtained timelapse imaging data of gastrulating

Indexed as

active and passive cell intercalationconvergent extensionself-organizationtissue mechanics

Identifiers

PMID37398061
PMCPMC10312603
OpenAlexW4378802360

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.