Evidence map›Paper›PMID 37398006›Full record

ArticlebioRxiv : the preprint server for biology2023

Pseudouridine guides germline small RNA transport and epigenetic inheritance.

Rowan P Herridge, Jakub Dolata, Valentina Migliori, Cristiane de Santis Alves, Filipe Borges, Andrea J Schorn, Frédéric Van Ex, Jean-Sebastien Parent, Ann Lin, Mateusz Bajczyk and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 4 countries.

Rowan P HerridgeHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.ORCID 0000-0002-4264-9292
Jakub DolataHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.ORCID 0000-0001-6141-8863
Valentina MiglioriThe Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.ORCID 0000-0003-4978-2245
Cristiane de Santis AlvesHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.
Filipe BorgesHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.ORCID 0000-0002-7388-2118
Andrea J SchornHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.
Frédéric Van ExHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.
Jean-Sebastien ParentHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.ORCID 0000-0001-7859-7415
Ann LinHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.
Mateusz BajczykDepartment of Gene Expression, Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, Poznan, Poland.ORCID 0000-0001-7043-2827
Tommaso LeonardiThe Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.ORCID 0000-0002-4449-1863
Alan HendrickStorm Therapeutics, Ltd., Moneta Building (B280), Babraham Research Campus, Cambridge CB22 3AT, UK.ORCID 0000-0002-8604-0462
Tony KouzaridesThe Gurdon Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.ORCID 0000-0002-8918-4162
Robert A MartienssenHoward Hughes Medical Institute, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 11724, USA.ORCID 0000-0003-1285-9608
Howard Hughes Medical Institute · USUniversity of Cambridge · GBAdam Mickiewicz University in Poznań · PL

Funding

Single-Cell Biology Shared ResourceP30CA045508 · NCI · COLD SPRING HARBOR LABORATORY · PI John Edward Moses · 1987 to 2026
$118.9M
RNAi, Histone Modification and the DDB1/CPSF-Like Complex Rik1R01GM076396 · NIGMS · COLD SPRING HARBOR LABORATORY · PI MARTIENSSEN, ROBERT A · 2007 to 2020
$4.9M
Transposons, RNA Interference and HeterochromatinR01GM067014 · NIGMS · COLD SPRING HARBOR LABORATORY · PI MARTIENSSEN, ROBERT A · 2003 to 2016
$4.1M
Cancer Research UK 27321NCI NIH HHS P30 CA045508NIGMS NIH HHS R01 GM067014NIGMS NIH HHS R01 GM076396
6 · The paper itself

Abstract

Epigenetic modifications that arise during plant and animal development, such as DNA and histone modification, are mostly reset during gamete formation, but some are inherited from the germline including those marking imprinted genes

Identifiers

PMID37398006
PMCPMC10312437
OpenAlexW4378951650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.