Evidence map›Paper›PMID 37397694›Full record

ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2023

A multi-strain probiotic promoted recovery of puppies from gastroenteritis in a randomized, double-blind, placebo-controlled study.

Rosa A Molina, Marcela D'Urso Villar, María H Miranda, Natalia C Maldonado, Graciela M Vignolo, María E F Nader-Macías

Open access · greenAbstract readRandomized Controlled Trial, Veterinary
In one paragraph

Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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  7. The Effect ofMicroorganisms · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rosa A MolinaCentro de Referencia para Lactobacilos (CERELA), CONICET, Chacabuco 145, (T4000) Tucumán, Argentina (Molina, Miranda, Maldonado, Vignolo, Nader-Macías); Facultad de Agronomía y Zootecnia (Molina) and Cátedra de Bioestadística, Facultad de Medicina (D'Urso Villar), Universidad Nacional de Tucumán (UNT), (T4000) Tucumán, Argentina.
Marcela D'Urso VillarCentro de Referencia para Lactobacilos (CERELA), CONICET, Chacabuco 145, (T4000) Tucumán, Argentina (Molina, Miranda, Maldonado, Vignolo, Nader-Macías); Facultad de Agronomía y Zootecnia (Molina) and Cátedra de Bioestadística, Facultad de Medicina (D'Urso Villar), Universidad Nacional de Tucumán (UNT), (T4000) Tucumán, Argentina.
María H MirandaCentro de Referencia para Lactobacilos (CERELA), CONICET, Chacabuco 145, (T4000) Tucumán, Argentina (Molina, Miranda, Maldonado, Vignolo, Nader-Macías); Facultad de Agronomía y Zootecnia (Molina) and Cátedra de Bioestadística, Facultad de Medicina (D'Urso Villar), Universidad Nacional de Tucumán (UNT), (T4000) Tucumán, Argentina.
Natalia C MaldonadoCentro de Referencia para Lactobacilos (CERELA), CONICET, Chacabuco 145, (T4000) Tucumán, Argentina (Molina, Miranda, Maldonado, Vignolo, Nader-Macías); Facultad de Agronomía y Zootecnia (Molina) and Cátedra de Bioestadística, Facultad de Medicina (D'Urso Villar), Universidad Nacional de Tucumán (UNT), (T4000) Tucumán, Argentina.
Graciela M VignoloCentro de Referencia para Lactobacilos (CERELA), CONICET, Chacabuco 145, (T4000) Tucumán, Argentina (Molina, Miranda, Maldonado, Vignolo, Nader-Macías); Facultad de Agronomía y Zootecnia (Molina) and Cátedra de Bioestadística, Facultad de Medicina (D'Urso Villar), Universidad Nacional de Tucumán (UNT), (T4000) Tucumán, Argentina.
María E F Nader-MacíasCentro de Referencia para Lactobacilos (CERELA), CONICET, Chacabuco 145, (T4000) Tucumán, Argentina (Molina, Miranda, Maldonado, Vignolo, Nader-Macías); Facultad de Agronomía y Zootecnia (Molina) and Cátedra de Bioestadística, Facultad de Medicina (D'Urso Villar), Universidad Nacional de Tucumán (UNT), (T4000) Tucumán, Argentina.
National University of Tucumán · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective and animals: Acute diarrhea is among the most common causes of veterinary consultations for dogs. A double-blind, placebocontrolled intervention trial was done with 120 puppies with gastroenteritis. These dogs were 1 to 4 mo old, male and female, of various breeds and sizes. Procedure: Dogs were randomly allocated into 2 groups: Those in the treated group (TG) received a multi-strain probiotic with Results: At the start of the trial, the 2 groups were similar. Probiotic administration for 7 d normalized fecal consistency, with 69, 50, and 80% of small, medium, and large puppies in the TG achieving a fecal score of 1 (separate hard lumps) at 7 d, significantly better than puppies in the CG. After 7 d of treatment, most puppies (70%) in the TG had an excellent recovery, whereas in the CG, recoveries were 35.7% "bad" and 30.4% "fair." Therefore, treatment with probiotics hastened recovery ( Conclusion: In a randomized, double-blind, placebo-controlled study, puppies with gastroenteritis symptoms receiving a multi-strain probiotic had rapid improvement, implying beneficial effects on the microbiota and its functionality.

Indexed as

Dog DiseasesGastroenteritisProbioticsAnimalsDiarrheaDogsDouble-Blind MethodFecesFemaleMale

Identifiers

PMID37397694
PMCPMC10286135
OpenAlexW4382918927

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.