Evidence map›Paper›PMID 37397588›Full record

ReviewWorld journal of critical care medicine2023

Approaches to neuroprotection in pediatric neurocritical care.

Angad Kochar, Kara Hildebrandt, Rebecca Silverstein, Brian Appavu

Abstract readReview
In one paragraph

Review in World journal of critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Angad KocharDepartment of Neurosciences, Phoenix Children's Hospital, Phoenix, AZ 85213, United States.
Kara HildebrandtDepartment of Neurosciences, Phoenix Children's Hospital, Phoenix, AZ 85213, United States.
Rebecca SilversteinDepartment of Neurosciences, Phoenix Children's Hospital, Phoenix, AZ 85213, United States.
Brian AppavuDepartment of Neurosciences, Phoenix Children's Hospital, Phoenix, AZ 85213, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute neurologic injuries represent a common cause of morbidity and mortality in children presenting to the pediatric intensive care unit. After primary neurologic insults, there may be cerebral brain tissue that remains at risk of secondary insults, which can lead to worsening neurologic injury and unfavorable outcomes. A fundamental goal of pediatric neurocritical care is to mitigate the impact of secondary neurologic injury and improve neurologic outcomes for critically ill children. This review describes the physiologic framework by which strategies in pediatric neurocritical care are designed to reduce the impact of secondary brain injury and improve functional outcomes. Here, we present current and emerging strategies for optimizing neuroprotective strategies in critically ill children.

Indexed as

Cerebral perfusionCerebrovascular pressure reactivityNeuroprotectionPediatric neurocritical care

Identifiers

PMID37397588
PMCPMC10308339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.