Evidence map›Paper›PMID 37397272›Full record

ArticleJournal of functional foods2023

Molecular networking identifies an AHR-modulating benzothiazole from white button mushrooms (

Xiaoling Chen, Andrew D Patterson, Gary H Perdew, Iain A Murray, Joshua J Kellogg

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of functional foods, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoling ChenDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, United States.
Andrew D PattersonDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, United States.
Gary H PerdewDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, United States.
Iain A MurrayDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, United States.
Joshua J KelloggDepartment of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, United States.

Funding

Activation of the Ah receptor and epithelial integrityR35ES028244 · NIEHS · PENNSYLVANIA STATE UNIVERSITY, THE · PI PERDEW, GARY H. · 2017 to 2024
$6.2M
Research Training in Physiological Adaptations to StressT32GM108563 · NIGMS · PENNSYLVANIA STATE UNIVERSITY, THE · PI CANTORNA, MARGHERITA T, KORZICK, DONNA HOPE · 2014 to 2023
$2.2M
Environmental Ah Receptor Ligand Impact on the Host-Microbiome Metabolic AxisR01ES028288 · NIEHS · PENNSYLVANIA STATE UNIVERSITY, THE · PI PATTERSON, ANDREW · 2017 to 2021
$1.7M
NIEHS NIH HHS R01 ES028288NIEHS NIH HHS R35 ES028244NIGMS NIH HHS T32 GM108563
6 · The paper itself

Abstract

Diet-derived aryl hydrocarbon receptor (AHR) ligands have potential to maintain gut health. However, among the myriad bioactive compounds from foods, identifying novel functional ligands which would significantly impact gastrointestinal health is a challenge. In this study, a novel AHR modulator is predicted, identified, and characterized in the white button mushroom (

Indexed as

Agaricus bisporusAHRAryl hydrocarbon receptorBiochemometricsMolecular networkingUntargeted metabolomicsWhite button mushroom

Identifiers

PMID37397272
PMCPMC10312048

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.