Evidence map›Paper›PMID 37397129›Full record

ArticleFrontiers in behavioral neuroscience2023

Examining the long-term effects of traumatic brain injury on fear extinction in male rats.

K A Smith, M R Raskin, M H Donovan, V Raghunath, S Mansoorshahi, M J Telch, J Shumake, L J Noble-Haeusslein, M H Monfils

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in behavioral neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

K A SmithDepartment of Psychology, The University of Texas at Austin, Austin, TX, United States.
M R RaskinDepartment of Psychology, The University of Texas at Austin, Austin, TX, United States.
M H DonovanDepartment of Neurology, Dell Medical School, The University of Texas at Austin, Austin, TX, United States.
V RaghunathDepartment of Psychology, The University of Texas at Austin, Austin, TX, United States.
S MansoorshahiDepartment of Psychology, The University of Texas at Austin, Austin, TX, United States.
M J TelchDepartment of Psychology, The University of Texas at Austin, Austin, TX, United States.
J ShumakeInstitute of Mental Health Research, The University of Texas at Austin, Austin, TX, United States.
L J Noble-HaeussleinDepartment of Psychology, The University of Texas at Austin, Austin, TX, United States.
M H MonfilsDepartment of Psychology, The University of Texas at Austin, Austin, TX, United States.
The University of Texas at Austin · USTexas Research Institute · US

Funding

Technology Development P2CHD086843 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AMBROSIO, FABRISIA · 2015 to 2024
$10.5M
NICHD NIH HHS P2C HD086843
6 · The paper itself

Abstract

There is a strong association between traumatic brain injuries (TBIs) and the development of psychiatric disorders, including post-traumatic stress disorder (PTSD). Exposure-based therapy is a first-line intervention for individuals who suffer from PTSD and other anxiety-related disorders; however, up to 50% of individuals with PTSD do not respond well to this approach. Fear extinction, a core mechanism underlying exposure-based therapy, is a procedure in which a repeated presentation of a conditioned stimulus in the absence of an unconditioned stimulus leads to a decrease in fear expression, and is a useful tool to better understand exposure-based therapy. Identifying predictors of extinction would be useful in developing alternative treatments for the non-responders. We recently found that CO

Indexed as

CO2extinctionfear conditioningindividual differencestraumatic brain injury

Identifiers

PMID37397129
PMCPMC10313105
OpenAlexW4380991802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.