Evidence map›Paper›PMID 37396799›Full record

ArticleEClinicalMedicine2023

Trends in the burden and determinants of hypertensive heart disease in the Eastern Mediterranean region, 1990-2019: an analysis of the Global Burden of Disease Study 2019.

Asieh Mansouri, Alireza Khosravi, Kamran Mehrabani-Zeinabad, Jacek A Kopec, Karam I I Adawi, Michelle Lui, Hanan F Abdul Rahim, Wagida Anwar, Ibtihal Fadhil, Kadhim Sulaiman and 16 more

Abstract read
In one paragraph

Article in EClinicalMedicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Observational
  2. Article
  3. Burden of hypertension-related diseases in Eastern Mediterranean region.Journal of Taibah University Medical Sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Asieh MansouriHypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Alireza KhosraviHypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Kamran Mehrabani-ZeinabadCardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Jacek A KopecSchool of Population & Public Health, University of British Columbia, Vancouver, Canada.
Karam I I AdawiDepartment of Public Health, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.
Michelle LuiSchool of Population & Public Health, University of British Columbia, Vancouver, Canada.
Hanan F Abdul RahimDepartment of Public Health, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.
Wagida AnwarCommunity Medicine Department, Faculty of Medicine, Ain Shams University, Egypt and Armed Forces College of Medicine (AFCM), Egypt.
Ibtihal FadhilEastern Mediterranean Non-Communicable Disease Alliance, Kuwait.
Kadhim SulaimanNational Heart Canter, Royal Hospital, Oman.
Nooshin BazarganiDepartment of Cardiology, Dubai Hospital, Dubai, United Arab Emirates.
Georges SaadeDepartment of Cardiology, Bellevue Medical Center, Beirut, Lebanon.
Hasan A FarhanScientific Council of Cardiology, Iraqi Board for Medical Specializations, Baghdad Heart Center, Baghdad, Iraq.
Wael AlMahmeedHeart and Vascular Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates.
Syedah Saira BokhariDepartment of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Nejat HassenSchool of Population & Public Health, University of British Columbia, Vancouver, Canada.
Amani AlandejaniSchool of Population & Public Health, University of British Columbia, Vancouver, Canada.
Shahin ShiraniDepartment of Cardiology, Tehran University of Medical Science, Dr Ali Shariati Hospital, Tehran, Iran.
Amr AbdinSyrian Cardiovascular Association, Damascus, Syria.
Yosef ManlaHeart and Vascular Institute, Cleveland Clinic Abu Dhabi, United Arab Emirates.
Catherine JohnsonInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Benjamin StarkInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Gregory A RothDivision of Cardiology, Department of Medicine, University of Washington, Seattle, USA.
Ali H MokdadInstitute for Health Metrics and Evaluation, University of Washington, Seattle, USA.
Sheikh Mohammed Shariful IslamInstitute for Physical Activity and Nutrition, Deakin University, Melbourne, Australia.
Nizal SarrafzadeganSchool of Population & Public Health, University of British Columbia, Vancouver, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypertensive heart disease (HHD), one of the end-organ damage consequences of hypertension, is an important public health issue worldwide. Data on the HHD burden in the Eastern Mediterranean region (EMR) are scarce. We aimed to investigate the burden of HHD in the EMR, its member countries, and globally from 1990 to 2019. Methods: We used 2019 Global Burden of Disease (GBD) data to report the HHD age-standardised prevalence, disability adjusted life years (DALYs), years of life lost (YLLs), and mortality, as well as HHD risk factors attribution percent with their 95% uncertainty interval (UI). Global data are reported alongside EMR data, and its 22 respective countries. We compared the burden of HHD by socio-demographic index (SDI), sex, age groups, and countries. Findings: The age-standardised prevalence rate (per 100,000 population) of HHD was higher in the EMR (281.7; 95% UI: 204.5-383.4) in 2019, compared with the global prevalence (233.8; 95% UI: 170.5-312.9). The EMR age-standardised DALYs (per 100,000 population) for HHD in 2019 was 561.9 (361.0-704.1), compared with 268.2 (204.6-298.1) at the global level. There was an increase in HHD prevalence, reduction in mortality, and DALYs between 1990 and 2019 (4.01%, -7.6%, and -6.5%, respectively) in EMR. Among EMR countries, the highest versus lowest rates of age-standardised prevalence, mortality, and DALYs in 2019 [estimate (95% UI)] were in Jordan [561.62 (417.9-747.6)] versus Saudi Arabia [94.9 (69.5-129.0)]; Afghanistan [74.5 (23.7-112.3)] versus Saudi Arabia [4.3 (3.3-5.9)]; and Afghanistan [1374.1 (467.2-2020.7)] versus Qatar [87.11 (64.40-114.29)], respectively. Interpretation: HHD remains a significant problem in the EMR, with a higher burden than global levels. Serious efforts toward high-quality management and prevention are strongly recommended. Based on this study, our recommendation for the EMR is to adopt effective preventive strategies. For example, promoting healthy dietary patterns and prompt screening for undiagnosed HTN in public places, promoting regular blood pressure measurements at home, and creating community awareness about early detection of HTN. Funding: None.

Indexed as

Disability-adjusted life yearsEastern Mediterranean regionGlobal burden of diseaseHypertensive heart diseaseYears of life lost

Identifiers

PMID37396799
PMCPMC10314131

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.