ArticleArchives of Razi Institute2023
Interleukin-1β rs1143634 Polymorphism and Susceptibility to Periodontitis in the Iraqi Population.
Article in Archives of Razi Institute, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 2 citations in OpenAlex.
- Interleukin-1 Polymorphisms in Caucasian Adults with Down Syndrome and Advanced Periodontitis: A Cross-Sectional Study.Dentistry journal · 2026Article
- Genetic Polymorphism ofJournal of clinical medicine · 2026Article
- Correlation of tumor necrosis factor-α and interleukin-1 single-nucleotide polymorphisms with the risk of migraine development.Frontiers in genetics · 2025Article
- The Impact ofDiagnostics (Basel, Switzerland) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis is a complex multifactorial inflammatory disease, and its genetic basis has been studied. The Interleukin-1 beta (IL-1β) is a crucial proinflammatory mediator in the pathogenesis of periodontitis with high polymorphism. This study aimed to investigate whether the rs1143634 genetic variant of the IL-1β gene is associated with an increased risk for periodontitis. For this purpose, genotyping of the IL-1β rs1143634 polymorphism was performed using the polymerase chain reaction-restriction fragment length polymorphism method on 90 patients within the age range of 35-60 years old. They were divided into two groups: 64 periodontitis cases (stage 3 and 4 periodontitis according to 2017 classification) and 26 racially matched healthy cases as the control group. Fisher's exact test showed a significant decrease in TT homozygous genotype in periodontitis cases, compared to the control group (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.