Evidence map›Paper›PMID 37396623›Full record

ArticleInternational journal of pharmaceutics: X2023

A case study on decentralized manufacturing of 3D printed medicines.

Iria Seoane-Viaño, Xiaoyan Xu, Jun Jie Ong, Ahmed Teyeb, Simon Gaisford, André Campos-Álvarez, Anja Stulz, Carmen Marcuta, Lilia Kraschew, Wolfgang Mohr and 2 more

Abstract read
In one paragraph

Article in International journal of pharmaceutics: X, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  15. Trend of pharmaceuticals 3D printing in the Middle East and North Africa (MENA) region: An overview, regulatory perspective and future outlook.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Iria Seoane-ViañoDepartment of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.
Xiaoyan XuDepartment of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.
Jun Jie OngDepartment of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.
Ahmed TeyebBrunel Innovation Centre, Brunel University London, Uxbridge UB8 3PH, UK.
Simon GaisfordDepartment of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.
André Campos-ÁlvarezFABRX Artificial Intelligence, Carretera de Escairón, 14, Currelos (O Saviñao), CP 27543, Spain.
Anja StulzLosan Pharma GmbH, Otto-Hahn-Strasse 13, 79395 Neuenburg, Germany.
Carmen MarcutaLosan Pharma GmbH, Otto-Hahn-Strasse 13, 79395 Neuenburg, Germany.
Lilia KraschewLosan Pharma GmbH, Otto-Hahn-Strasse 13, 79395 Neuenburg, Germany.
Wolfgang MohrLosan Pharma GmbH, Otto-Hahn-Strasse 13, 79395 Neuenburg, Germany.
Abdul W BasitDepartment of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.
Alvaro GoyanesDepartment of Pharmaceutics, UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmaceutical 3D printing (3DP) is one of the emerging enabling technologies of personalised medicines as it affords the ability to fabricate highly versatile dosage forms. In the past 2 years, national medicines regulatory authorities have held consultations with external stakeholders to adapt regulatory frameworks to embrace point-of-care manufacturing. The proposed concept of decentralized manufacturing (DM) involves the provision of feedstock intermediates (pharma-inks) prepared by pharmaceutical companies to DM sites for manufacturing into the final medicine. In this study, we examine the feasibility of this model, with respect to both manufacturing and quality control. Efavirenz-loaded granulates (0-35%

Indexed as

Additive manufacturing of drug products and drug delivery systemsDecentralised and distributed fabrication of formulationsDigital healthcare and industry 4.0Direct powder extrusion of personalized pharmaceuticalsProcess analytical technologiesReal-time release testingThree-dimensional printing using M3DIMAKER

Identifiers

PMID37396623
PMCPMC10314212

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.