Evidence map›Paper›PMID 37396466›Full record

ArticleCardiology research and practice2023

Outcomes of Combined Heart-Kidney Transplantation in Older Recipients.

Curry Sherard, Vineeth Sama, Jennie H Kwon, Khaled Shorbaji, Lauren V Huckaby, Brett A Welch, Chakradhari Inampudi, Ryan J Tedford, Arman Kilic

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cardiology research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Curry SherardCollege of Medicine, Medical University of South Carolina, Charleston, SC, USA.ORCID https://orcid.org/0000-0002-5547-5156
Vineeth SamaCollege of Medicine, Medical University of South Carolina, Charleston, SC, USA.
Jennie H KwonDivision of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, SC, USA.
Khaled ShorbajiDivision of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, SC, USA.ORCID https://orcid.org/0000-0002-9371-9350
Lauren V HuckabyDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Brett A WelchDivision of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, SC, USA.
Chakradhari InampudiDepartment of Cardiology, Medical University of South Carolina, Charleston, SC, USA.
Ryan J TedfordDepartment of Cardiology, Medical University of South Carolina, Charleston, SC, USA.
Arman KilicDivision of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, SC, USA.ORCID https://orcid.org/0000-0001-8112-8345

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The upper limit of recipient age for combined heart-kidney transplantation (HKT) remains controversial. This study evaluated the outcomes of HKT in patients aged ≥65 years. Methods: The United Network of Organ Sharing (UNOS) was used to identify patients undergoing HKT from 2005 to 2021. Patients were stratified by age at transplantation: <65 and ≥ 65 years. The primary outcome was one-year mortality. Secondary outcomes included 90-day and 5-year mortality, postoperative new-onset dialysis, postoperative stroke, acute rejection prior to discharge, and rejection within one-year of HKT. Survival was compared using Kaplan-Meier analysis, and risk adjustment for mortality was performed using Cox proportional hazards modeling. Results: HKT in recipients aged ≥65 significantly increased from 5.6% of all recipients in 2005 to 23.7% in 2021 ( Conclusion: Combined HKT is increasing in older recipients, and advanced age ≥65 should not preclude HKT.

Identifiers

PMID37396466
PMCPMC10314816

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