Evidence map›Paper›PMID 37396422›Full record

ArticleJACC. Asia2023

Clinical Outcomes of Calcium-Channel Blocker vs Beta-Blocker: From the Korean Acute Myocardial Infarction Registry.

Moo Hyun Kim, Song Lin Yuan, Kwang Min Lee, Xuan Jin, Zhao Yan Song, Young-Rak Cho, Michael S Lee, Ju Han Kim, Myung Ho Jeong, Investigators for KAMIR

Abstract read
In one paragraph

Article in JACC. Asia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
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  4. Article
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Observational
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Moo Hyun KimDepartment of Cardiology, Dong-A University Hospital, Busan, Republic of Korea.
Song Lin YuanDepartment of Cardiology, Dong-A University Hospital, Busan, Republic of Korea.
Kwang Min LeeDepartment of Cardiology, Dong-A University Hospital, Busan, Republic of Korea.
Xuan JinDepartment of Cardiology, Dong-A University Hospital, Busan, Republic of Korea.
Zhao Yan SongDepartment of Cardiology, Dong-A University Hospital, Busan, Republic of Korea.
Young-Rak ChoDepartment of Cardiology, Dong-A University Hospital, Busan, Republic of Korea.
Michael S LeeDivision of Cardiology, UCLA Medical Center, Los Angeles, California, USA.
Ju Han KimDepartment of Internal Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.
Myung Ho JeongDepartment of Internal Medicine, Chonnam National University Hospital, Gwangju, Republic of Korea.
Investigators for KAMIR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Although current guidelines recommend beta-blockers (BBs) after acute myocardial infarction (AMI), the role of calcium-channel blockers (CCBs) has not been well investigated, especially nondihydropyridine. Objectives: This study aimed to compare the effects of CCBs on cardiovascular outcomes compared with BBs in AMI because patients from East Asia have a higher incidence of a vasospastic angina component compared with Western countries. Methods: Among 15,628 patients enrolled in the KAMIR-V (Korean Acute Myocardial Infarction Registry-V), we evaluated 10,650 in-hospital survivors who were treated with either CCBs or BBs. We applied a propensity score for 1:4 pair matching of baseline covariates and Cox regression to compare CCBs and BBs. The primary endpoint was all-cause death at 1 year. The secondary endpoints were 1-year major adverse cardiac and cerebrovascular events, which was the composite of cardiac death, myocardial infarction, revascularization, and readmission due to heart failure and stroke. Results: There was a significant interaction with the treatment arm with left ventricular ejection fraction (LVEF) ( Conclusions: CCB therapy did not increase adverse cardiovascular events for patients after AMI with preserved LVEF. CCBs can be considered as an alternative for BBs in East Asian patients after AMI with preserved LVEF.

Indexed as

acute myocardial infarctionbeta-blockercalcium-channel blockerclinical outcomes

Identifiers

PMID37396422
PMCPMC10308128

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.