Evidence map›Paper›PMID 37396303›Full record

ArticleFrontiers in cellular and infection microbiology2023

A conserved epitope in VAR2CSA is targeted by a cross-reactive antibody originating from

Uwa Iyamu, Daniel Ferrer Vinals, Bernard Tornyigah, Eliana Arango, Rakesh Bhat, Trixie Rae Adra, Simranjit Grewal, Kimberly Martin, Amanda Maestre, Michael Overduin and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Current update on malaria in pregnancy: a systematic review.Tropical diseases, travel medicine and vaccines · 2025
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Uwa IyamuSchool of Public Health, University of Alberta, Edmonton, AB, Canada.
Daniel Ferrer VinalsSchool of Public Health, University of Alberta, Edmonton, AB, Canada.
Bernard TornyigahSchool of Public Health, University of Alberta, Edmonton, AB, Canada.
Eliana ArangoGrupo Salud y Comunidad, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Rakesh BhatDepartment of Biochemistry, University of Alberta, Edmonton, AB, Canada.
Trixie Rae AdraDepartment of Biochemistry, University of Alberta, Edmonton, AB, Canada.
Simranjit GrewalDepartment of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada.
Kimberly MartinSchool of Public Health, University of Alberta, Edmonton, AB, Canada.
Amanda MaestreGrupo Salud y Comunidad, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Michael OverduinDepartment of Biochemistry, University of Alberta, Edmonton, AB, Canada.
Bart HazesDepartment of Medical Microbiology and Immunology, University of Alberta, Edmonton, AB, Canada.
Stephanie K YanowSchool of Public Health, University of Alberta, Edmonton, AB, Canada.
University of Alberta · CAUniversidad de Antioquia · CO

Funding

Exploiting cross-reactive, conserved epitopes in Plasmodium vivax to develop a vaccine against falciparum placental malaria.R01AI150944 · NIAID · UNIVERSITY OF ALBERTA · PI YANOW, STEPHANIE · 2020 to 2025
$1.9M
NIAID NIH HHS R01 AI150944
6 · The paper itself

Abstract

During

Indexed as

Malaria, FalciparumMalaria, VivaxAnimalsAntibodies, ProtozoanAntigens, ProtozoanChondroitin SulfatesEpitopesErythrocytesFemaleMicePlacentaPlasmodium falciparumPlasmodium vivaxPregnancyProtein BindingRatsAntibodies, ProtozoanAntigens, ProtozoanChondroitin SulfatesEpitopescross-reactivitymalariapeptidepregnancyPvDBPvaccine designVAR2CSA

Identifiers

PMID37396303
PMCPMC10312377
OpenAlexW4380992446

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.