Evidence map›Paper›PMID 37396300›Full record

ArticleJournal of oral microbiology2023

Exploration of the interplay between spatially distinct microbial habitats through comparative analysis.

Hyunji Kim, Jin-Sil Hong, Pil-Young Yun, Kyung-Gyun Hwang, Keun-Suh Kim, Hyo-Jung Lee, Kyoung Un Park

Open access · goldAbstract read
In one paragraph

Article in Journal of oral microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hyunji KimDepartment of Laboratory Medicine, Seoul National University Bundang Hospital and Seoul National University College of Medicine, Seoul, Republic of Korea.
Jin-Sil HongDepartment of Periodontology, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Pil-Young YunDepartment of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Kyung-Gyun HwangDivision of Oral and Maxillofacial Surgery, Department of Dentistry, College of Medicine, Hanyang University, Seoul, Republic of Korea.
Keun-Suh KimDepartment of Periodontology, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Hyo-Jung LeeDepartment of Periodontology, Section of Dentistry, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.ORCID https://orcid.org/0000-0002-0439-7389
Kyoung Un ParkDepartment of Laboratory Medicine, Seoul National University Bundang Hospital and Seoul National University College of Medicine, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-2402-7633
Seoul National University Bundang Hospital · KRHanyang University · KRSeoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The oral microbiome is closely associated with systemic diseases, indicating the presence of bacteremia and inflammatory mediators in the systemic circulation. Our research aims to investigate the relationship between the oral microbiome and other microbial habitats. Methods: We analyzed 180 specimens from 36 patients, including saliva, buccal swab, plaque, stool, and blood samples from a healthy group (Non_PD, Results: PD saliva showed significant richness differences (P's < 0.05), similar to plaque. Buccal swabs had slight variations. Microbial network analysis revealed altered microbial interactions in the PD group, with decreased interactions in saliva and buccal swabs, and increased interactions in plaque. In our analysis of nine specimens where all paired habitat samples could be analyzed, microorganisms linked to oral periodontitis were found in sterile blood samples, resembling the oral cavity's composition. Conclusions: Microbiome differences should consider overall microbial-environment interactions, alongside diversity and richness. Our data cautiously suggest that disease-related changes in the salivary microbiome may be reflected in blood specimens through the oral-blood axis.

Indexed as

bloodgenomicshabitatMicrobiomeperiodontitisplaquesaliva

Identifiers

PMID37396300
PMCPMC10308874
OpenAlexW4382402694

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.