Evidence map›Paper›PMID 37396224›Full record

ArticleACS omega2023

Korean Amberjack Skin-Inspired Hyaluronic Acid Bioink for Reconstruction of Human Skin.

Hoai-Thuong Duc Bui, Wanho Cho, Jae Keun Park, Moon Sue Lee, Hong Kee Kim, Hyuk Sang Yoo

Abstract read
In one paragraph

Article in ACS omega, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hoai-Thuong Duc BuiDepartment of Medical Biomaterials Engineering, Kangwon National University, Chuncheon 24341, Republic of Korea.
Wanho ChoDepartment of Medical Biomaterials Engineering, Kangwon National University, Chuncheon 24341, Republic of Korea.
Jae Keun ParkDepartment of Medical Biomaterials Engineering, Kangwon National University, Chuncheon 24341, Republic of Korea.
Moon Sue LeeR&D center, InnoTherapy Inc., Seoul 07282, Republic of Korea.
Hong Kee KimR&D center, InnoTherapy Inc., Seoul 07282, Republic of Korea.
Hyuk Sang YooDepartment of Medical Biomaterials Engineering, Kangwon National University, Chuncheon 24341, Republic of Korea.ORCID https://orcid.org/0000-0002-4346-9154

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Decellularized extracellular matrix (dECM) has been extensively employed as tissue engineering scaffolds because its components can greatly enhance the migration and proliferation of cultivating cells. In this study, we decellularized Korean amberjack skin and incorporated soluble fractions in hyaluronic acid hydrogels with 3D-printed tissue engineering hydrogels to overcome any limitation of animal-derived dECM. The hydrolyzed fish-dECM was mixed with methacrylated hyaluronic acid and chemically crosslinked to 3D-printed fish-dECM hydrogels, where fish-dECM contents affected both printability and injectability of the hydrogels. Swelling ratios and mass erosion of the 3D-printed hydrogels were dependent on fish-dECM contents, where higher fish-dECM in the hydrogel increased swelling ratios and mass erosion rates. The higher content of fish-dECM considerably enhanced the viability of the incorporated cells in the matrix for 7 days. Artificial human skin was constructed by seeding human dermal fibroblasts and keratinocytes in the 3D-printed hydrogels, and a formation of a bilayered skin was visualized with tissue staining. Thus, we envision that 3D-printed hydrogels containing fish-dECM can be an alternative bioink composed of a non-mammal-derived matrix.

Identifiers

PMID37396224
PMCPMC10308565

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.