Evidence map›Paper›PMID 37396097›Full record

ReviewEcancermedicalscience2023

Colorectal cancer in Tanzania: the current status and future directions.

Larry Akoko, Nathan Brand, Vihar Kotecha, Sam Byabato, Jerry Ndumbalo, Masumbuko Mwashambwa, Amos Mwakigonja, Ann Lowry

Abstract readReview
In one paragraph

Review in Ecancermedicalscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Barriers to Radiotherapy Access in Sub-Saharan Africa for Patients with Cancer: A Systematic Review.International journal of environmental research and public health · 2024
    Pooled it
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Larry AkokoDepartment of Surgery, Muhimbili University for Health and Allied Sciences, PO Box 65001, Dar es Salaam, Tanzania.
Nathan BrandDepartment of Surgery, Muhimbili University for Health and Allied Sciences, PO Box 65001, Dar es Salaam, Tanzania.
Vihar KotechaDepartment of Surgery, Catholic University for Health and Allied Sciences, PO Box 1464, Mwanza, Tanzania.
Sam ByabatoDepartment of Surgery, Catholic University for Health and Allied Sciences, PO Box 1464, Mwanza, Tanzania.
Jerry NdumbaloClinical Oncology Department, Ocean Road Cancer Institute, PO Box 3592, Dar es Salaam, Tanzania.
Masumbuko MwashambwaDepartment of Surgery, University of Dodoma School of Medicine and Dentistry, Dodoma 41218, Tanzania.
Amos MwakigonjaDepartment of Pathology, Muhimbili University for Health and Allied Sciences, PO Box 65001, Dar es Salaam, Tanzania.
Ann LowryDepartment of Surgery, University of Minnesota, Minneapolis, MN 55455, USA.

Funding

University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
FIC NIH HHS D43 TW009343
6 · The paper itself

Abstract

Introduction: Globally, colorectal cancer (CRC) is the third most common malignancy and the second most common cause of cancer death. By 2030, the incidence is expected to increase to reach 2.2 million cases and 1.1 million deaths. In Sub-Saharan Africa, accurate cancer incidence data is limited, but anecdotally, clinicians note a significant rise in the incidence of CRC in the past decade. To educate clinicians on the growing burden of CRC, the Tanzanian Surgical Association hosted a 4-day CRC symposium from 3rd to 6th October 2022. Following the meeting, a group of multidisciplinary stakeholders created a working group whose first task was to assess the epidemiology, presentation and available resources for CRC care in Tanzania. The findings of that assessment are described in this article. Findings: The true incidence of CRC in Tanzania is currently unknown. However, individual high-volume centres have noted a dramatic rise in cases of colon and rectal cancer on their wards. A review of the published data on CRC in Tanzania showed that most patients present with CRC late and the limited availability of endoscopic and diagnostic services poses a challenge for accurately staging these patients prior to treatment. Multidisciplinary care, including surgery, chemotherapy and radiation, is available for the treatment of CRC in Tanzania, although the capacity and quality of these services vary throughout the country. Conclusion: There is a substantial burden of CRC in Tanzania that appears to be increasing. While there is capacity in the country to provide all aspects of multidisciplinary care, late presentation, limited access to diagnostic and treatment services and poor coordination continue to be significant barriers to providing optimal treatment to these patients.

Indexed as

cancer in LMICcolorectal cancerglobal oncologyglobal pathologyglobal surgeryTanzania

Identifiers

PMID37396097
PMCPMC10310332

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.