Evidence map›Paper›PMID 37396009›Full record

ReviewAnnals of gastroenterology

Gut microbial metabolites and its impact on human health.

Shahrose Rahman, Amber L O'Connor, Sarah L Becker, Ranish K Patel, Robert G Martindale, Vassiliki Liana Tsikitis

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Lipopolysaccharide-mediated macrophage polarization, conserved pathogenesis, and implications for peripheral neuropathy: a systematic review.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Pooled it
  2. Nutrients · 2026
    Trial
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  17. Vitamin BCommunications biology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shahrose RahmanDepartment of Surgery, Oregon Health and Science University, Portland, OR, USA.
Amber L O'ConnorDepartment of Surgery, Oregon Health and Science University, Portland, OR, USA.
Sarah L BeckerDepartment of Surgery, Oregon Health and Science University, Portland, OR, USA.
Ranish K PatelDepartment of Surgery, Oregon Health and Science University, Portland, OR, USA.
Robert G MartindaleDepartment of Surgery, Oregon Health and Science University, Portland, OR, USA.
Vassiliki Liana TsikitisDepartment of Surgery, Oregon Health and Science University, Portland, OR, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the primary methods by which the gut microbiome interacts with its host is through the interactions that occur through the production of the metabolites produced, either directly, or indirectly, through microbial metabolism. Decades of research has demonstrated that these metabolic products play a vital role in human health, either for its benefit or detriment. This review article highlights the main metabolites produced by the interactions between diet and the gut microbiome, bile acids and the gut microbiome, and products produced by the gut microbiome alone. Additionally, this article reviews the literature on the effects that these metabolites play on human health.

Indexed as

bile acidsGut metabolitesmicrobiomeshort chain fatty acidstrimethylamine-N-oxide

Identifiers

PMID37396009
PMCPMC10304525

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.