Evidence map›Paper›PMID 37395947›Full record

ArticleApplied biochemistry and biotechnology2024

Antineoplastic Effects of Mucuna pruriens Against Human Colorectal Adenocarcinoma.

Sagar Seetharamaiah, Vidya Shimoga Muddappa, Manjunatha Bukkambudhi Krishnaswamy, Rashmi Kanugodu Vasappa

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In one paragraph

Article in Applied biochemistry and biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Therapeutic assessment ofFrontiers in oncology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sagar SeetharamaiahDepartment of Biotechnology, Sir M Visvesvaraya Institute of Technology, International Airport Road, Hunasamaranahalli, Bengaluru, 562157, Karnataka, India.
Vidya Shimoga MuddappaDepartment of Biotechnology Engineering, NMAM Institute of Technology - Affiliated to NITTE (Deemed to Be University), Nitte, 574110, India.ORCID http://orcid.org/0000-0003-1319-7466
Manjunatha Bukkambudhi KrishnaswamyDepartment of Biotechnology, Oxford College of Engineering, 10Th Milestone, Hosur Road, Bangalore, 560068, India.ORCID http://orcid.org/0000-0001-6994-5182
Rashmi Kanugodu VasappaDepartment of Biotechnology, Sir M Visvesvaraya Institute of Technology, International Airport Road, Hunasamaranahalli, Bengaluru, 562157, Karnataka, India. rashmi_biotech@sirmvit.edu.ORCID http://orcid.org/0000-0002-6545-1983
Oxford Dental College and Hospital · INVisvesvaraya Technological University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucuna pruriens (MP) which is commonly known as "Velvet Bean" is an underutilized legume traditionally used to treat Parkinson's disease and male fertility issues. Extracts of MP have also been identified for their antidiabetic, antioxidant, and antineoplastic effects. Commonly, the antioxidant and anticancer properties of a drug are linked together as antioxidants scavenge free radicals and prevent the cellular DNA damage which could result in cancer development. In this investigation, comparative assessment of the anticancer and antioxidant potentials of methanolic seed extracts from two common varieties of MP, Mucuna pruriens var. pruriens (MPP) and Mucuna pruriens var. utilis (MPU) against human colorectal cancer adenocarcinoma cells COLO-205, was carried out. The highest antioxidant potential was recorded with MPP with an IC

Indexed as

AdenocarcinomaAntineoplastic AgentsColorectal NeoplasmsMucunaAntioxidantsHumansMalePlant ExtractsSeedsAntineoplastic AgentsAntioxidantsPlant ExtractsAnticancerAntioxidantApoptosisHuman colorectal carcinomaMucuna pruriensp53 gene

Identifiers

PMID37395947
OpenAlexW4382919392

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.