Evidence map›Paper›PMID 37395934›Full record

Trial reportJournal of cancer survivorship : research and practice2024

Quality of life and symptom burden after rectal cancer surgery: a randomised controlled trial comparing patient-led versus standard follow-up.

Ida Hovdenak, Henriette Vind Thaysen, Inge Thomsen Bernstein, Peter Christensen, Ann Hauberg, Lene Hjerrild Iversen, Christoffer Johansen, Susie Lindhardt Larsen, Søren Laurberg, Anders Husted Madsen and 4 more

Abstract readRandomized Controlled TrialComparative StudyMulticenter Study
In one paragraph

Trial report in Journal of cancer survivorship : research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ida HovdenakDepartment of Surgery, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark. idajak@rm.dk.ORCID 0000-0003-4979-5863
Henriette Vind ThaysenDepartment of Surgery, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Inge Thomsen BernsteinDepartment of Gastrointestinal Surgery, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Peter ChristensenDepartment of Surgery, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Ann HaubergDepartment of Gastrointestinal Surgery, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Lene Hjerrild IversenDepartment of Surgery, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Christoffer JohansenLate Effect Research Unit, Oncology Clinic, University Hospital Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
Susie Lindhardt LarsenDepartment of Surgery, Regional Hospital Gødstrup, Hospitalsparken 15, 7400, Herning, Denmark.
Søren LaurbergDepartment of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Anders Husted MadsenDepartment of Clinical Medicine, Aarhus University, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.
Mogens Rørbæk MadsenDepartment of Surgery, Regional Hospital Gødstrup, Hospitalsparken 15, 7400, Herning, Denmark.
Helle Vindfeldt RasmussenDepartment of Gastrointestinal Surgery, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Ole Thorlacius-UssingDepartment of Gastrointestinal Surgery, Clinical Cancer Research Unit, Aalborg University Hospital, Hobrovej 18-22, 9000, Aalborg, Denmark.
Therese JuulDepartment of Surgery, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.

Funding

Kræftens Bekæmpelse R97-A6511-14-S23
6 · The paper itself

Abstract

purposeAfter curatively intended rectal cancer (RC) surgery, new follow-up strategies are warranted, seeking more individualised care and targeting health-related quality of life (HRQoL) and functional outcomes. The FURCA trial aimed to investigate the effect of patient-led follow-up on HRQoL and symptom burden 3 years after surgery.

methodsRC patients from four Danish centres were randomised 1:1 to intervention (patient-led follow-up with patient education and self-referral to a specialist nurse) or control (standard follow-up with five routine doctor visits). Patients in both groups had a computed tomography (CT) at 1 and 3 years. The primary outcome (HRQoL) was assessed by the Functional Assessment of Cancer Therapy - colorectal (FACT-C) score (Ward et al. in Qual Life Res. 8(3):181-95, 18). Secondary outcomes were functional measures, patient involvement and satisfaction and cancer recurrence at 3 years.

resultsFrom Feb 2016 to Aug 2018, 336 patients were included of whom 248 completed 3 years of follow-up. Between-group differences were found neither for the primary endpoint, nor for functional outcomes. The recurrence rate did not differ between the groups. Patient involvement and satisfaction were higher in the intervention group with statistical significance in almost half of the items.

conclusionsWe found no effect on HRQoL and symptom burden from patient-led follow-up, although it may improve patient-perceived involvement and satisfaction. IMPLICATIONS FOR CANCER SURVIVORS: The findings in this study suggest that patient-led follow-up is a more tailored approach to meet cancer survivors' needs and might improve their ability to cope with survivorship. CLINICALTRIALS: GOV IDENTIFIER: R97-A6511-14-S23.

Indexed as

Quality of LifeRectal NeoplasmsAgedCancer SurvivorsDenmarkFemaleFollow-Up StudiesHumansMaleMiddle AgedSymptom BurdenHealth-related quality of lifeLate sequelaePatient-led follow-upRectal cancer

Identifiers

PMID37395934
PMCPMC11424718

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.