Evidence map›Paper›PMID 37395919›Full record

ArticleInsights into imaging2023

Photon-counting CT allows better visualization of temporal bone structures in comparison with current generation multi-detector CT.

Robert Hermans, Lukas Boomgaert, Lesley Cockmartin, Joke Binst, Rashèl De Stefanis, Hilde Bosmans

Registry-linked trialAbstract read
In one paragraph

Article in Insights into imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07603167 (p-PHOTOLARYNX- ANTHEM), which is not on this map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07603167 enrolling by invitationnot on this mapstarted 2025, after this paper: background citation

p-PHOTOLARYNX- ANTHEM: Pilot Photon-Counting CT Evaluation of the Paraglottic Space and Cartilage Involvement in Laryngeal Cancer

TypeobservationalSponsorHumanitas UniversityRan2025 to 2027Enrolled60ConditionsLaryngeal Cancer, Laryngeal CarcinomaArmsPhoton Counting Computed Tomography
3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Improved assessment of the cochlear implant and temporal bone structures with ultra-high resolution photon-counting detector CT compared to conventional CT systems.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  10. Preoperative Imaging for Cochlear Implantation: A Global Consensus.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
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  13. Observational
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  16. Comprehensive Review of Inner Ear Anatomy on Photon-Counting CT.AJNR. American journal of neuroradiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Robert HermansDepartment of Radiology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium. robert.hermans@uzleuven.be.ORCID http://orcid.org/0000-0002-9935-5543
Lukas BoomgaertDepartment of Radiology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
Lesley CockmartinDepartment of Radiology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
Joke BinstDepartment of Radiology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
Rashèl De StefanisDepartment of Radiology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
Hilde BosmansDepartment of Radiology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare photon-counting CT (PCCT) and multi-detector CT (MDCT) for visualization of temporal bone anatomic structures.

methodsThirty-six exams of temporal bones without pathology were collected from consecutive patients on a MDCT, and another 35 exams on a PCCT scanner. Two radiologists independently scored visibility of 14 structures for the MDCT and PCCT dataset, using a 5-point Likert scale, with a 2-month wash-out period. For MDCT, the acquisition parameters were: 110 kV, 64 × 0.6 mm (slice thickness reconstructed to 0.4 mm), pitch 0.85, quality ref. mAs 150, and 1 s rotation time; for PCCT: 120 kV, 144 × 0.2 mm, pitch 0.35, IQ level 75, and 0.5 s rotation time. Patient doses were reported as dose length product values (DLP). Statistical analysis was done using the Mann-Whitney U test, visual grading characteristic (VGC) analysis, and ordinal regression.

resultsSubstantial agreement was found between readers (intraclass correlation coefficient 0.63 and 0.52 for MDCT and PCCT, resp.). All structures were scored higher for PCCT (p < 0.0001), except for Arnold's canal (p = 0.12). The area under the VGC curve was 0.76 (95% CI, 0.73-0.79), indicating a significantly better visualization on PCCT. Ordinal regression showed the odds for better visualization are 354 times higher (95% CI, 75-1673) in PCCT (p < 0.0001). Average (range) of DLP was 95 (79-127) mGy*cm for MDCT and 74 (50-95) mGy*cm for PCCT (p < 0.001).

conclusionPCCT provides a better depiction of temporal bone anatomy than MDCT, at a lower radiation dose. CRITICAL RELEVANCE STATEMENT: PCCT provides a better depiction of temporal bone anatomy than MDCT, at a lower radiation dose. KEY POINTS: 1. PCCT allows high-resolution imaging of temporal bone structures. 2. Compared to MDCT, the visibility of normal temporal bone structures is scored better with PCCT. 3. PCCT allows to obtain high-quality CT images of the temporal bones at lower radiation doses than MDCT.

Indexed as

Computed tomographyPhoton-counting CTRadiation doseTemporal bone imaging

Identifiers

PMID37395919
PMCPMC10317909

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.