Evidence map›Paper›PMID 37395907›Full record

ArticleInternational ophthalmology2023

Changes in choroidal tissue post-supplementation with vitamin D in pediatric patients who are deficient in vitamin D.

Funda Kocaay, Abdurrahman Bilen, Abdulvahit Asik, Şerife Şule Çınar, Emre Aydemir, Gözde Aksoy Aydemir, Ali Karnaz, Veysel Cankurtaran

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Article in International ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Funda KocaayDepartment of Public Health, Faculty of Medicine, Ankara Medipol University, Ankara, Turkey. fkocaay@gmail.com.ORCID http://orcid.org/0000-0003-4352-4675
Abdurrahman BilenDepartment of Ophthalmology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey.
Abdulvahit AsikDepartment of Pediatrics, Adıyaman University Education and Research Hospital, Adıyaman, Turkey.
Şerife Şule ÇınarDepartment of Ophthalmology, DünyaGöz Hospital, Serdivan, Sakarya, Turkey.
Emre AydemirDepartment of Ophthalmology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey.
Gözde Aksoy AydemirDepartment of Ophthalmology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey.
Ali KarnazDepartment of Ophthalmology, Nizip State Hospital, Gaziantep, Turkey.
Veysel CankurtaranDepartment of Ophthalmology, Hatay MustafaKemal University, Antakya, Hatay, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo quantitatively assess the choroidal structural parameters of patients in the pediatric age group who were deficient in vitamin D [Vit-D] pre- and post-treatment.

designProspective, case-control study.

methodsChoroidal structural parameters, including the choroidal thickness (CT) at five points, total choroidal area (TA), luminal choroidal area (LA), stromal choroidal area (SA), and choroidal vascular index (CVI), in patients in the pediatric age group who were deficient in Vit-D, in Group 1, and those who were not, in Group 2, were compared. The patients were divided into 3 different groups according to how deficient in Vit-D they were. This was re-evaluated after treatment.

resultsGroup 1 consisted of 83 patients and group 2 consisted of 85 patients. CT at all five points, and the TA, SA, LA, and CVI, were lower in Group 1. And for all of these, a significant increase was seen post-treatment. While a significant increase was observed in all of the values in the group with the most severe deficiency in Vit-D, significant changes were observed in the TA, LA, SA, and CVI values in the group that was mildly deficient in Vit-D. There was no significant post-treatment value in the CT values (except for the Temporal 1500 CT [P = 0.012]).

conclusionDecreases in the CT, TA, LA, SA, and CVI were among the structural changes that were seen to occur in the pediatric patient group that was deficient in Vit-D. Moreover, thinning of the choroid and a decrease in the CVI were the most significant in the group with the greatest Vit-D deficiency.

Indexed as

Tomography, Optical CoherenceVitamin DCase-Control StudiesChildChoroidDietary SupplementsHumansProspective StudiesVisual AcuityVitaminsVitamin DVitaminsChoroidal thicknessChoroidal vascular indexOptical coherence tomographyVitamin D deficiency

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.