Evidence map›Paper›PMID 37395742›Full record

ArticleDento maxillo facial radiology2023

Maximum and mean standardized uptake values of medication-related osteonecrosis of the jaw with bone SPECT/CT: comparison of mandibular pathologies, control and temporomandibular joints.

Yasuhito Tezuka, Ichiro Ogura

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Article in Dento maxillo facial radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

2 authors.

Yasuhito TezukaQuantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.
Ichiro OguraQuantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.ORCID 0000-0002-9169-8429

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecently, single-photon emission CT/CT (SPECT/CT) plays an important role in assessing patients with medication-related osteonecrosis of the jaw (MRONJ). The aim of this study was to investigate maximum and mean standardized uptake values (SUVs) of MRONJ with bone SPECT/CT, especially comparison of mandibular pathologies, control and temporomandibular joints.

methods61 mandibular patients with MRONJ who underwent bone SPECT/CT were included in this study. The maximum and mean SUVs of the lesion, right and left sides of the lesion, opposite side of the lesion as control, right and left temporomandibular joints were analyzed using a workstation and software. The SUVs of MRONJ were analyzed using one-way analysis of variance with Tukey's honestly significant difference test. Patient characteristics with MRONJ and SUVs were analyzed using Mann-Whitney

resultsThe maximum and mean SUVs for opposite side of the lesions (4.4 ± 2.0 and 1.8 ± 0.7) were significantly lower than those for mandibular lesions (18.3 ± 8.1 and 6.3 ± 2.8), right side of the lesions (8.1 ± 3.9 and 2.9 ± 1.3) and left side of the lesions (8.1 ± 3.9 and 2.8 ± 1.4), respectively. The maximum and mean SUVs for right and left sides of the lesions, and opposite side of the lesions, right and left temporomandibular joints were not significant difference. Furthermore, the maximum SUVs of the mandibular lesions were a significant difference for age and staging.

conclusionsThe maximum and mean SUVs with SPECT/CT can be useful in the quantitative management of MRONJ patients.

Indexed as

Bisphosphonate-Associated Osteonecrosis of the JawBone Density Conservation AgentsHumansMandibleTemporomandibular JointTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedBone Density Conservation AgentsBisphosphonate-associated osteonecrosis of the jawDentistryNuclear medicineSingle photon emission computed tomography computed tomography

Identifiers

PMID37395742
PMCPMC10461260

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