Evidence map›Paper›PMID 37395685›Full record

ArticleJournal of chemical information and modeling2023

Arginine Residues Modulate the Membrane Interactions of pHLIP Peptides.

Tomás F D Silva, Hannah Visca, Craig Klumpp, Oleg A Andreev, Yana K Reshetnyak, Miguel Machuqueiro

Open access · hybridAbstract read
In one paragraph

Article in Journal of chemical information and modeling, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Improving the Estimation of pThe journal of physical chemistry. B · 2026
    Article
  2. Rescue of Epilepsy-Associated Mutations of the Highly Conserved Glycine Residue 443 in the Human GABA Transporter 1.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Tomás F D SilvaBioISI─Instituto de Biossistemas e Ciências Integrativas, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.ORCID 0000-0003-4608-2673
Hannah ViscaPhysics Department, University of Rhode Island, Kingston, Rhode Island 02881 United States.
Craig KlumppPhysics Department, University of Rhode Island, Kingston, Rhode Island 02881 United States.
Oleg A AndreevPhysics Department, University of Rhode Island, Kingston, Rhode Island 02881 United States.
Yana K ReshetnyakPhysics Department, University of Rhode Island, Kingston, Rhode Island 02881 United States.
Miguel MachuqueiroBioISI─Instituto de Biossistemas e Ciências Integrativas, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisboa, Portugal.ORCID 0000-0001-6923-8744
University of Rhode Island · USScuola Internazionale Superiore di Studi Avanzati · ITUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most processes at the water-membrane interface often involve protonation events in proteins or peptides that trigger important biological functions and events. This is the working principle behind the pHLIP peptide technology. A key titrating aspartate (Asp14 in

Indexed as

Aspartic AcidLipid BilayersHydrogen-Ion ConcentrationMembrane ProteinsPeptidesAspartic AcidLipid BilayersMembrane ProteinsPeptidespHLIP protein

Identifiers

PMID37395685
PMCPMC10369490
OpenAlexW4382919429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.