Evidence map›Paper›PMID 37395644›Full record

ArticleJournal of clinical microbiology2023

Determination of MIC Quality Control Ranges for Ceftibuten-Avibactam (Fixed 4 μg/mL), a Novel β-Lactam/β-Lactamase Inhibitor Combination.

Michael D Huband, Kelley A Fedler, Helio S Sader, Gregory G Stone, Mariana Castanheira

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. A Review ofInternational journal of microbiology · 2026
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael D HubandJMI Laboratories, North Liberty, Iowa, USA.ORCID 0000-0002-9769-9019
Kelley A FedlerJMI Laboratories, North Liberty, Iowa, USA.
Helio S SaderJMI Laboratories, North Liberty, Iowa, USA.ORCID 0000-0001-7022-6644
Gregory G StonePfizer Inc., New York, New York, USA.
Mariana CastanheiraJMI Laboratories, North Liberty, Iowa, USA.ORCID 0000-0003-0126-1782
JMI Laboratories · USPfizer (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ceftibuten/ARX-1796 (avibactam prodrug) is a novel oral antibacterial combination in early clinical development for the treatment of complicated urinary tract infections (cUTI) including pyelonephritis. ARX-1796 is the novel avibactam prodrug being combined with ceftibuten for oral dosing that is converted to active avibactam

Indexed as

beta-Lactamase InhibitorsProdrugsAnti-Bacterial AgentsAzabicyclo Compoundsbeta-LactamasesCeftibutenEscherichia coliHumansKlebsiella pneumoniaeLactamsMicrobial Sensitivity TestsQuality ControlAnti-Bacterial AgentsavibactamAzabicyclo Compoundsbeta-Lactamase Inhibitorsbeta-LactamasesCeftibutenLactamsProdrugsavibactamceftibutenM23quality control

Identifiers

PMID37395644
PMCPMC10358160
OpenAlexW4382918563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.