Evidence map›Paper›PMID 37394624›Full record

ReviewArchives of toxicology2023

Progress and promise of alternative animal and non-animal methods in biomedical research.

Irlan Almeida Freires, David Fernando Colon Morelo, Lélio Fernando Ferreira Soares, Isabela Silva Costa, Leonardo Pereira de Araújo, Isadora Breseghello, Henrique Ballassini Abdalla, Josy Goldoni Lazarini, Pedro Luiz Rosalen, Suzane Cristina Pigossi and 1 more

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Archives of toxicology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Assessment of theToxicon: X · 2024
    Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Irlan Almeida FreiresDepartment of Biosciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil. irlan.almeida@gmail.com.ORCID http://orcid.org/0000-0002-1079-6941
David Fernando Colon MoreloInstitute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, University of Bonn, Bonn, Germany.
Lélio Fernando Ferreira SoaresSchool of Dentistry, Federal University of Alfenas, Alfenas, Brazil.
Isabela Silva CostaSchool of Dentistry, Federal University of Alfenas, Alfenas, Brazil.
Leonardo Pereira de AraújoSchool of Pharmaceutical Sciences, Federal University of Alfenas, Alfenas, Brazil.
Isadora BreseghelloSchool of Dentistry, Federal University of Alfenas, Alfenas, Brazil.
Henrique Ballassini AbdallaLaboratory of Neuroimmune Interface of Pain Research, São Leopoldo Mandic Institute and Research Center, Campinas, SP, Brazil.
Josy Goldoni LazariniDepartment of Biosciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil.
Pedro Luiz RosalenDepartment of Biosciences, Piracicaba Dental School, University of Campinas, Piracicaba, SP, Brazil.
Suzane Cristina PigossiSchool of Dentistry, Federal University of Alfenas, Alfenas, Brazil.
Marcelo FranchinSchool of Dentistry, Federal University of Alfenas, Alfenas, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell culture and invertebrate animal models reflect a significant evolution in scientific research by providing reliable evidence on the physiopathology of diseases, screening for new drugs, and toxicological tests while reducing the need for mammals. In this review, we discuss the progress and promise of alternative animal and non-animal methods in biomedical research, with a special focus on drug toxicity.

Indexed as

Biomedical ResearchAnimalsMammalsModels, Animal3D cell cultureBrine Shrimp (Artemia salina)Fruit fly (Drosophila melanogaster)Galleria mellonella larvaeRoundworms (Caenorhabditis elegans)Zebrafish

Identifiers

PMID37394624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.