Evidence map›Paper›PMID 37394507›Full record

ArticlePediatrics2023

Acceptability and Feasibility of Saliva-delivered PCR Coronavirus 2019 Tests for Young Children.

Rebecca E Lee, Michael Todd, Hyunsung Oh, SeungYong Han, Michelle Santana, Jaquelyn Aguilar-Troncoso, Meg Bruening, Joanna L Kramer, Tomás León, Vel Murugan and 2 more

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05178290 (Back to ECE Safely With SAGE), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05178290 nacompletednot on this map

Back to ECE Safely With SAGE: Reducing COVID-19 Transmission in Hispanic and Low-income Preschoolers

TypeinterventionalSponsorArizona State UniversityRan2021 to 2023Enrolled1,356ConditionsCOVID-19 Testing, Children, Preschool, Parents, Child DevelopmentArmsCHILD back-to-ECE COVID-19 saliva testing, ECE personnel back-to-ECE COVID-19 saliva screening, SAGE garden programming
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Diagnostic Accuracy of Molecular Testing on Saliva and Oral Swabs for Pulmonary Tuberculosis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Rebecca E LeeCenter for Health Promotion and Disease Prevention, Edson College of Nursing and Health Innovation.
Michael ToddEdson College of Nursing and Health Innovation.
Hyunsung OhSchool of Social Work, Watts College of Public Service and Community Solutions, Arizona State University, Phoenix, Arizona.
SeungYong HanEdson College of Nursing and Health Innovation.
Michelle SantanaCenter for Health Promotion and Disease Prevention, Edson College of Nursing and Health Innovation.
Jaquelyn Aguilar-TroncosoCenter for Health Promotion and Disease Prevention, Edson College of Nursing and Health Innovation.
Meg BrueningDepartment of Nutritional Sciences, College of Health and Human Development, The Pennsylvania State University, University Park, Pennsylvania.
Joanna L KramerPhoenix Children's Hospital, Division of Primary, Complex, and Adolescent Medicine, Phoenix, Arizona.
Tomás LeónEquality Health Foundation, Phoenix, Arizona.
Vel MuruganCenter for Personalized Diagnostics, ASU Biodesign Clinical Testing Laboratory, Biodesign Institute, Arizona State University, Tempe, Arizona.
Hector ValdezCenter for Health Promotion and Disease Prevention, Edson College of Nursing and Health Innovation.
Michelle Villegas-GoldOffice of the Vice President of Research, Arizona State University, Tempe, Arizona.
Arizona State University · USPennsylvania State University · USPhoenix Children's Hospital · US

Funding

Back to ECE Safely with SAGE: Reducing COVID-19 Transmission in Hispanic and Low-income PreschoolersOT2HD108101 · NICHD · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI LEE, REBECCA ELIZABETH · 2021 to 2022
$3.9M
NICHD NIH HHS OT2 HD108101
6 · The paper itself

Abstract

objectivesAccess to readily available, reliable, and easy-to-use coronavirus disease 2019 (COVID-19) tests remains critical, despite great vaccination progress. Universal back-to-school testing offered at early care and education ([ECE]; ie, preschool) sites to screen for positive cases may help preschoolers safely return to, and stay in, ECE. We examined the acceptability and feasibility of using a quantitative polymerase chain reaction COVID-19 saliva test for young children (n = 227, 54.0% girls: mean age = 52.3 ± 8.1 months) and their caregivers (n = 70 teachers: mean = 36.6 ± 14.7 years; n = 227 parents: mean = 35.5 ± 9.1 years) to mitigate the spread of COVID-19 and reduce days of school and work missed for households with children who test positive.

methodsParticipants were recruited at ECE sites serving low-income communities as part of the Rapid Acceleration of Diagnostic Testing-Underserved Populations Back to Early Care and Education Safely with Sustainability via Active Garden Education project (NCT05178290).

resultsSurveys in English or Spanish administered at testing events to children and caregivers at ECE sites showed child and adult acceptability and feasibility ratings were generally high. More favorable child and parent ratings were positively associated with child age and whether the child was able to produce a saliva sample. Language preference was not associated with any outcomes.

conclusionsSaliva sampling for COVID-19 at ECE sites is an acceptable strategy as an additional layer of protection for 4- and 5-year-olds; however, alternate testing strategies may be needed for younger children.

Indexed as

COVID-19AdultChildChild, PreschoolCOVID-19 TestingFeasibility StudiesFemaleHumansMalePolymerase Chain ReactionSalivaSurveys and Questionnaires

Identifiers

PMID37394507
PMCPMC10312283
OpenAlexW4382918408

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.