Evidence map›Paper›PMID 37393982›Full record

ArticleExperimental cell research2023

Deficiency in homologous recombination is associated with changes in cell cycling and morphology in Saccharomyces cerevisiae.

Cory L Holland, Monica F Weis, Corbin J England, Armand M Berry, Paige D Hall, L Kevin Lewis

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental cell research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Deep structure-function analysis of the endonuclease Mus81 with dominant mutational scanning.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cory L HollandChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, USA.
Monica F WeisChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, USA.
Corbin J EnglandChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, USA.
Armand M BerryChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, USA.
Paige D HallChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, USA.
L Kevin LewisChemistry and Biochemistry, Texas State University, 601 University Drive, San Marcos, TX, 78666, USA. Electronic address: LL18@txstate.edu.
Texas State University · US

Funding

DNA repair pathways preserve cellular homeostasisR15GM139093 · NIGMS · TEXAS STATE UNIVERSITY · PI LEWIS, LYSLE KEVIN · 2020 to 2020
$440k
NIGMS NIH HHS R15 GM139093
6 · The paper itself

Abstract

Exposure of eukaryotic cells to ionizing radiation or clastogenic chemicals leads to formation of DNA double-strand breaks (DSBs). These lesions are also generated internally by chemicals and enzymes, in the absence of exogenous agents, though the sources and consequences of such endogenously generated DSBs remain poorly understood. In the current study, we have investigated the impact of reduced recombinational repair of endogenous DSBs on stress responses, cell morphology and other physical properties of S. cerevisiae (budding yeast) cells. Use of phase contrast and DAPI-based fluorescence microscopy combined with FACS analysis confirmed that recombination-deficient rad52 cell cultures exhibit chronically high levels of G

Indexed as

Saccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsCell CycleDNA-Binding ProteinsDNA RepairHomologous RecombinationRad51 RecombinaseDNA-Binding ProteinsRad51 RecombinaseSaccharomyces cerevisiae ProteinsCell cycleCheckpointDNA repairLight scatteringRecombinationReplicationSedimentation

Identifiers

PMID37393982
PMCPMC11770826
OpenAlexW4382655249

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.