Evidence map›Paper›PMID 37393904›Full record

ArticleUrologia internationalis2023

Succinate Dehydrogenase Defects Giant Renal Cell Carcinoma.

Xia Sun, Guang Wang, Ziye Huang, Pei Li, Bowei Yang, Tianyun Wang, Jiongming Li

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Urologia internationalis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. [Succinate Dehydrogenase-Deficient Renal Cell Carcinoma: Clinicopathological Analysis of 11 Cases].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xia SunThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Guang WangThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Ziye HuangThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China, 438272075@qq.com.
Pei LiThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Bowei YangThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Tianyun WangThe Department of Pathology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.
Jiongming LiThe Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (RCC) is a new subtype of RCC included in the 2016 edition of the WHO classification in RCC. SDH-defective RCC accounts for 0.05-0.2%, and preoperative diagnosis is difficult. We report a severe adherent RCC of inferior vena cava that underwent open radical nephrectomy after preoperative renal artery embolization. Postoperative histopathological examination diagnosed SDH-defective RCC; the clinicopathological stage was pT2b. After 10 months of follow-up, the patient had no evidence of disease recurrence. For patients with large RCC, interventional embolization can be selected to reduce intraoperative bleeding and blood transfusion, and it is recommended to complete interventional surgery within 3-4 h before surgery. SDH-deficient RCC is difficult to distinguish from other renal tumors in imaging, so immunohistochemical examination of SDHB is recommended for young and middle-aged patients, especially those under 45.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsHumansKidneyMiddle AgedNeoplasm Recurrence, LocalNephrectomySuccinate DehydrogenaseVena Cava, InferiorSuccinate DehydrogenaseRenal artery embolizationRenal cell carcinomaSuccinate dehydrogenase

Identifiers

PMID37393904
PMCPMC10614438

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.