Evidence map›Paper›PMID 37393539›Full record

ArticleThe British journal of radiology2023

Pancreatic neuroendocrine tumor: prediction of tumor grades by radiomics models based on ultrasound images.

Yi Dong, Dao-Hui Yang, Xiao-Fan Tian, Wen-Hui Lou, Han-Zhang Wang, Sheng Chen, Yi-Jie Qiu, Wenping Wang, Christoph F Dietrich

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Yi DongDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Dao-Hui YangDepartment of ultrasound, Xiamen Branch, Zhongshan Hospital, Fudan University, Xiamen, China.
Xiao-Fan TianDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Wen-Hui LouDepartment of Pancreatic Surgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Han-Zhang WangPrecision Health Institute, GE Healthcare China, Shanghai, China.
Sheng ChenDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Yi-Jie QiuDepartment of Ultrasound, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai, China.
Wenping WangDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China.
Christoph F DietrichDepartment General Internal Medicine, Hirslanden Clinics Beau-Site, Salem and Permancence, Bern, Switzerland.
Fudan University · CNZhongshan Hospital · CNHirslanden Klinik Beau-Site · CHUnited Imaging Healthcare (China) · CNXinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to investigate whether the radiomics analysis based on B-mode ultrasound (BMUS) images could predict histopathological tumor grades in pancreatic neuroendocrine tumors (pNETs).

methodsA total of 64 patients with surgery and histopathologically confirmed pNETs were retrospectively included (34 male and 30 female, mean age 52.4 ± 12.2 years). Patients were divided into training cohort (

resultsFinally, 18 G1 pNETs, 35 G2 pNETs, and 11 G3 pNETs patients were included. The radiomic score derived from BMUS images to predict G2/G3 from G1 displayed a good performance with an area under the receiver operating characteristic curve of 0.844 in the training cohort, and 0.833 in the testing cohort. The radiomic score achieved an accuracy of 81.8% in the training cohort and 80.0% in the testing cohort, a sensitivity of 0.750 and 0.786, a specificity of 0.833 and 0.833 in the training/testing cohorts. Clinical benefit of the score also exhibited superior usefulness of the radiomic score, as shown by the decision curve analysis.

conclusionsRadiomic data constructed from BMUS images have the potential for predicting histopathological tumor grades in patients with pNETs. ADVANCES IN KNOWLEDGE: The radiomic model constructed from BMUS images has the potential for predicting histopathological tumor grades and Ki-67 proliferation indexes in patients with pNETs.

Indexed as

Neuroectodermal Tumors, PrimitiveNeuroendocrine TumorsPancreatic NeoplasmsAdultFemaleHumansKi-67 AntigenMaleMiddle AgedNeoplasm GradingRetrospective StudiesKi-67 Antigen

Identifiers

PMID37393539
PMCPMC10461281
OpenAlexW4382881416

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.