ArticleThe British journal of radiology2023
Role of computed tomography in predicting adrenal adenomas with cortisol hypersecretion.
Article in The British journal of radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 7 citations in OpenAlex.
- Is a Reduction of Contralateral Adrenal Volume Assessed by CT Volumetry a Predictor of Autonomous Cortisol Secretion in Patients With Adrenal Incidentalomas?Journal of medical imaging and radiation oncology · 2026Article
- A comprehensive approach to the CT detection and evaluation of large adrenal masses (≥ 4 cm) part 1: benign adrenal lesions.Abdominal radiology (New York) · 2026Review
- Article
- A mediastinal eosinophilic adenoma misdiagnosed as an esophageal stromal tumor: A case report.Journal of cardiothoracic surgery · 2025Article
- Differentiation of multiple adrenal adenoma subtypes based on a radiomics and clinico-radiological model: a dual-center study.BMC medical imaging · 2025Article
- Clinical and imaging presentations are associated with function in incidental adrenocortical adenomas: a retrospective cohort study.European journal of endocrinology · 2024Article
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4 authors at 2 institutions in 1 country.
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Abstract
objectivesTo investigate performance of adrenal CT-derived multivariate prediction models in differentiating adenomas with cortisol hypersecretion from the other subtypes.
methodsThis retrospective study included 127 patients who underwent adrenal CT and had a surgically proven adrenal adenoma. Adenoma subtypes were defined according to biochemical test results: Group A, overt cortisol hypersecretion; Group B, mild cortisol hypersecretion; Group C, aldosterone hypersecretion; and Group D, non-function. Two independent readers analyzed size, attenuation, and washout properties of adenomas, and performed quantitative and qualitative analyses for assessing contralateral adrenal atrophy. Actual and internally validated areas under the curves (AUCs) of adrenal CT-derived multivariate prediction models for differentiating adenomas with cortisol hypersecretion from the other subtypes were assessed.
resultsIn differentiating Group A from the other groups, the actual and internally validated AUCs of the prediction model were 0.856 (95% confidence interval [CI]: 0.786, 0.926) and 0.847 (95% CI: 0.695, 0.999) for Reader 1, respectively, and 0.901 (95% CI: 0.845, 0.956) and 0.897 (95% CI: 0.783, 1.000) for Reader 2, respectively. In differentiating Group B from groups C and D, the actual and internally validated AUCs of the prediction model were 0.777 (95% CI: 0.687, 0.866) and 0.760 (95% CI: 0.552, 0.969) for Reader 1, respectively, and 0.783 (95% CI: 0.690, 0.875) and 0.765 (95% CI: 0.553, 0.977) for Reader 2, respectively.
conclusionAdrenal CT may be useful in differentiating adenomas with cortisol hypersecretion from the other subtypes. ADVANCES IN KNOWLEDGE: Adrenal CT may benefit in adrenal adenoma subtyping.
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