Evidence map›Paper›PMID 37393383›Full record

ArticleScientific reports2023

Medical transformer for multimodal survival prediction in intensive care: integration of imaging and non-imaging data.

Firas Khader, Jakob Nikolas Kather, Gustav Müller-Franzes, Tianci Wang, Tianyu Han, Soroosh Tayebi Arasteh, Karim Hamesch, Keno Bressem, Christoph Haarburger, Johannes Stegmaier and 3 more

Abstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  7. Assessment of transformer-based AI in clinical oncology.BMC medical informatics and decision making · 2025
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  18. AI approaches for the discovery and validation of drug targets.Cambridge prisms. Precision medicine · 2024
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Firas KhaderDepartment of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany. fkhader@ukaachen.de.
Jakob Nikolas KatherDepartment of Medicine III, University Hospital Aachen, Aachen, Germany.
Gustav Müller-FranzesDepartment of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany.
Tianci WangDepartment of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany.
Tianyu HanPhysics of Molecular Imaging Systems, Experimental Molecular Imaging, RWTH Aachen University, Aachen, Germany.
Soroosh Tayebi ArastehDepartment of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany.
Karim HameschDepartment of Medicine III, University Hospital Aachen, Aachen, Germany.
Keno BressemDepartment of Radiology, Charité-University Medicine Berlin, Berlin, Germany.
Christoph HaarburgerOcumeda GmbH, Munich, Germany.
Johannes StegmaierInstitute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany.
Christiane KuhlDepartment of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany.
Sven Nebelung *Department of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany.
Daniel Truhn *Department of Diagnostic and Interventional Radiology, University Hospital Aachen, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When clinicians assess the prognosis of patients in intensive care, they take imaging and non-imaging data into account. In contrast, many traditional machine learning models rely on only one of these modalities, limiting their potential in medical applications. This work proposes and evaluates a transformer-based neural network as a novel AI architecture that integrates multimodal patient data, i.e., imaging data (chest radiographs) and non-imaging data (clinical data). We evaluate the performance of our model in a retrospective study with 6,125 patients in intensive care. We show that the combined model (area under the receiver operating characteristic curve [AUROC] of 0.863) is superior to the radiographs-only model (AUROC = 0.811, p < 0.001) and the clinical data-only model (AUROC = 0.785, p < 0.001) when tasked with predicting in-hospital survival per patient. Furthermore, we demonstrate that our proposed model is robust in cases where not all (clinical) data points are available.

Indexed as

Critical CareDiagnostic ImagingArea Under CurveElectric Power SuppliesHumansRetrospective Studies

Identifiers

PMID37393383
PMCPMC10314902

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.