Evidence map›Paper›PMID 37393282›Full record

ArticleRadiation oncology (London, England)2023

Improving accelerated 3D imaging in MRI-guided radiotherapy for prostate cancer using a deep learning method.

Ji Zhu, Xinyuan Chen, Yuxiang Liu, Bining Yang, Ran Wei, Shirui Qin, Zhuanbo Yang, Zhihui Hu, Jianrong Dai, Kuo Men

Abstract read
In one paragraph

Article in Radiation oncology (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ji Zhu *National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Xinyuan Chen *National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Yuxiang LiuNational Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Bining YangNational Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Ran WeiNational Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Shirui QinNational Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Zhuanbo YangNational Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Zhihui HuNational Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Jianrong DaiNational Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
Kuo MenNational Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China. menkuo126@126.com.

Funding

National Natural Science Foundation of China 11975313National Natural Science Foundation of China 12005302
6 · The paper itself

Abstract

purposeThis study was to improve image quality for high-speed MR imaging using a deep learning method for online adaptive radiotherapy in prostate cancer. We then evaluated its benefits on image registration.

methodsSixty pairs of 1.5 T MR images acquired with an MR-linac were enrolled. The data included low-speed, high-quality (LSHQ), and high-speed low-quality (HSLQ) MR images. We proposed a CycleGAN, which is based on the data augmentation technique, to learn the mapping between the HSLQ and LSHQ images and then generate synthetic LSHQ (synLSHQ) images from the HSLQ images. Five-fold cross-validation was employed to test the CycleGAN model. The normalized mean absolute error (nMAE), peak signal-to-noise ratio (PSNR), structural similarity index measurement (SSIM), and edge keeping index (EKI) were calculated to determine image quality. The Jacobian determinant value (JDV), Dice similarity coefficient (DSC), and mean distance to agreement (MDA) were used to analyze deformable registration.

resultsCompared with the LSHQ, the proposed synLSHQ achieved comparable image quality and reduced imaging time by ~ 66%. Compared with the HSLQ, the synLSHQ had better image quality with improvement of 57%, 3.4%, 26.9%, and 3.6% for nMAE, SSIM, PSNR, and EKI, respectively. Furthermore, the synLSHQ enhanced registration accuracy with a superior mean JDV (6%) and preferable DSC and MDA values compared with HSLQ.

conclusionThe proposed method can generate high-quality images from high-speed scanning sequences. As a result, it shows potential to shorten the scan time while ensuring the accuracy of radiotherapy.

Indexed as

Deep LearningProstatic NeoplasmsRadiation OncologyHumansImaging, Three-DimensionalMagnetic Resonance ImagingMale1.5 T MR-linacAccelerated 3D MRI scanningCycle-consistent adversarial networksDeep learningHigh-quality MRI imageImage quality

Identifiers

PMID37393282
PMCPMC10314402

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.